iPTMnet Report for Q13133 (NR1H3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13133 / NR1H3_HUMAN
Protein Name Oxysterols receptor LXR-alpha
Gene Name Name: NR1H3
Synonyms:LXRA;
Organism Homo sapiens (Human)

PRO ID PR:Q13133
DAG View
PRO Name oxysterols receptor LXR-alpha (human)
Definition An oxysterols receptor LXR-alpha that is encoded in the genome of human.
Short Label hNR1H3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13133 (NR1H3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S29 O-Glycosylation GlyGen 29577901
S30 O-Glycosylation GlyGen 29577901
S36 O-Glycosylation GlyGen 29577901
S37 O-Glycosylation GlyGen 29577901
S49 O-Glycosylation GlyGen 29435130, 29577901, 19933273
S198 Phosphorylation PhosphoSitePlus   RLIMS-P   Signor 16904112, 18250151
S198 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus   Signor 18250151
S246 Phosphorylation PhosphoSitePlus
Y306 Phosphorylation PhosphoSitePlus
S310 Phosphorylation PhosphoSitePlus
S312 Phosphorylation PhosphoSitePlus
T314 Phosphorylation PhosphoSitePlus
K328 Sumoylation PhosphoSitePlus
S413 Phosphorylation PhosphoSitePlus
K434 Sumoylation PhosphoSitePlus
K434 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T314 I314 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]