iPTMnet Report for Q13126 (MTAP)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13126 / MTAP_HUMAN
Protein Name S-methyl-5'-thioadenosine phosphorylase
Gene Name Name: MTAP
Synonyms:MSAP;
Organism Homo sapiens (Human)

PRO ID PR:Q13126
DAG View
PRO Name S-methyl-5'-thioadenosine phosphorylase (human)
Definition An S-methyl-5'-thioadenosine phosphorylase that is encoded in the genome of human.
Short Label hMTAP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13126 (MTAP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation PhosphoSitePlus
T5 Phosphorylation PhosphoSitePlus
T6 Phosphorylation PhosphoSitePlus
T7 Phosphorylation PhosphoSitePlus
T8 Phosphorylation PhosphoSitePlus
K32 Ubiquitination PhosphoSitePlus
K40 Ubiquitination PhosphoSitePlus
K49 Ubiquitination PhosphoSitePlus
R60 Methylation PhosphoSitePlus
K71 Ubiquitination PhosphoSitePlus
C131 S-Nitrosylation dbSNO 26338901
T155 Phosphorylation IEDB 35494241
K157 Ubiquitination PhosphoSitePlus
C163 Methylation IEDB 31844290
K166 Ubiquitination PhosphoSitePlus
S183 Phosphorylation phospho.ELM   PhosphoSitePlus 15302935
T188 Phosphorylation phospho.ELM   PhosphoSitePlus 15302935
R235 Methylation PhosphoSitePlus
K248 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T7 Phosphorylation HPRD 20068231
S183 Phosphorylation HPRD 15302935
T188 Phosphorylation HPRD 15302935


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T5 I5 Biomuta DOID:4159 / skin cancer [ cosmic ]
T7 A7 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K49 T49 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K166 E166 Biomuta DOID:2531 / hematologic cancer [ cosmic ]