iPTMnet Report for Q13123 (IK)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13123 / RED_HUMAN
Protein Name Protein Red
Gene Name Name: IK
Synonyms:RED;
Organism Homo sapiens (Human)

PRO ID PR:Q13123
DAG View
PRO Name protein Red (human)
Definition A protein Red that is encoded in the genome of human.
Short Label hIK
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13123 (IK) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S6 Phosphorylation HPRD   PhosphoSitePlus 20068231
S10 Phosphorylation PhosphoSitePlus
K30 Ubiquitination PhosphoSitePlus
K38 Sumoylation PhosphoSitePlus
K38 Ubiquitination PhosphoSitePlus
T42 Phosphorylation HPRD   PhosphoSitePlus 20068231
T48 O-Glycosylation GlyGen 31373491
T48 Phosphorylation HPRD   PhosphoSitePlus 20068231
S49 O-Glycosylation GlyGen 31373491
K54 Acetylation PhosphoSitePlus
K54 Ubiquitination PhosphoSitePlus
K83 Acetylation PhosphoSitePlus
K83 Ubiquitination PhosphoSitePlus
K98 Acetylation PhosphoSitePlus   UniProt 19608861
K98 Ubiquitination PhosphoSitePlus
K112 Ubiquitination PhosphoSitePlus
Y114 Phosphorylation PhosphoSitePlus
T117 Phosphorylation PhosphoSitePlus
K137 Acetylation PhosphoSitePlus
S138 Phosphorylation PhosphoSitePlus
K142 Ubiquitination PhosphoSitePlus
K151 Sumoylation PhosphoSitePlus
K151 Ubiquitination PhosphoSitePlus
K164 Ubiquitination PhosphoSitePlus
K173 Sumoylation PhosphoSitePlus
K173 Ubiquitination PhosphoSitePlus
K191 Ubiquitination PhosphoSitePlus
K198 Ubiquitination PhosphoSitePlus
K205 Sumoylation PhosphoSitePlus
K205 Ubiquitination PhosphoSitePlus
K209 Ubiquitination PhosphoSitePlus
K224 Sumoylation PhosphoSitePlus
Y247 Phosphorylation PhosphoSitePlus
K260 Ubiquitination PhosphoSitePlus
T270 Phosphorylation PhosphoSitePlus
S287 Phosphorylation PhosphoSitePlus   UniProt 23186163
K303 Acetylation PhosphoSitePlus
K305 Acetylation PhosphoSitePlus
K310 Sumoylation PhosphoSitePlus
K310 Ubiquitination PhosphoSitePlus
Y325 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S328 Phosphorylation PhosphoSitePlus
T329 Phosphorylation PhosphoSitePlus
T330 Phosphorylation PhosphoSitePlus
K331 Ubiquitination PhosphoSitePlus
T332 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S382 Phosphorylation PhosphoSitePlus
Y383 Phosphorylation PhosphoSitePlus
K386 Acetylation PhosphoSitePlus
K388 Sumoylation PhosphoSitePlus
K404 Sumoylation PhosphoSitePlus
K404 Ubiquitination PhosphoSitePlus
K408 Acetylation PhosphoSitePlus
K408 Sumoylation PhosphoSitePlus
K408 Ubiquitination PhosphoSitePlus
S409 Phosphorylation PhosphoSitePlus
K413 Sumoylation PhosphoSitePlus
K413 Ubiquitination PhosphoSitePlus
S417 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 20068231
C448 Methylation IEDB 31844290
T452 Phosphorylation HPRD   phospho.ELM 18669648
S460 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 18669648, 18452278
Y466 Phosphorylation PhosphoSitePlus
T485 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17525332, 18077418
Y489 Phosphorylation PhosphoSitePlus
Y492 Phosphorylation PhosphoSitePlus
K501 Sumoylation PhosphoSitePlus
K501 Ubiquitination PhosphoSitePlus
Y506 Phosphorylation PhosphoSitePlus
K509 Ubiquitination PhosphoSitePlus
R514 Methylation PhosphoSitePlus
K520 Methylation PhosphoSitePlus
K520 Ubiquitination PhosphoSitePlus
R530 Methylation PhosphoSitePlus
K534 Ubiquitination PhosphoSitePlus
S536 Phosphorylation PhosphoSitePlus   UniProt 23186163
K541 Ubiquitination PhosphoSitePlus
K544 Sumoylation PhosphoSitePlus
K553 Sumoylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S6 C6 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S6 N6 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K137 R137 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
S382 N382 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K386 R386 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
K408 E408 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
R514 W514 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
K520 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
R530 H530 Biomuta DOID:1319 / brain cancer [ cosmic ]
R530 C530 Biomuta DOID:4159 / skin cancer [ cosmic ]
K534 T534 Biomuta DOID:263 / kidney cancer [ cosmic ]