iPTMnet Report for Q13118 (KLF10)
Protein Information
UniProt AC / UniProt ID | Q13118 / KLF10_HUMAN |
Protein Name | Krueppel-like factor 10 |
Gene Name | Name: KLF10 Synonyms:TIEG,TIEG1; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q13118 |
PRO Name | krueppel-like factor 10 (human) |
Definition | A krueppel-like factor 10 that is encoded in the genome of human. |
Short Label | hKLF10 |
Category | organism-gene |
Q13118 (KLF10) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K32 | Ubiquitination | score1 | PhosphoSitePlus | |||
T66 | Phosphorylation | score1 | PhosphoSitePlus | |||
T93 | Phosphorylation | P04049 (RAF1) | score3 | PhosphoSitePlus RLIMS-P | 23994618 | |
S97 | Phosphorylation | score1 | PhosphoSitePlus | |||
K135 | Sumoylation | score1 | PhosphoSitePlus | |||
K139 | Ubiquitination | score1 | PhosphoSitePlus | |||
S140 | Phosphorylation | score1 | PhosphoSitePlus | |||
K149 | Sumoylation | score1 | PhosphoSitePlus | |||
K149 | Ubiquitination | score1 | PhosphoSitePlus | |||
S184 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S206 | Phosphorylation | P24941 (CDK2) | score3 | PhosphoSitePlus RLIMS-P+ | 25728284 | |
K223 | Ubiquitination | score1 | PhosphoSitePlus | |||
S249 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 16964243 | ||
S351 | Phosphorylation | score1 | PhosphoSitePlus | |||
K356 | Ubiquitination | score1 | PhosphoSitePlus | |||
K378 | Ubiquitination | score1 | PhosphoSitePlus | |||
S383 | Phosphorylation | score1 | PhosphoSitePlus | |||
S384 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 20953893 | ||
K387 | Ubiquitination | score1 | PhosphoSitePlus | |||
T392 | Phosphorylation | score1 | PhosphoSitePlus | |||
T394 | Phosphorylation | score1 | PhosphoSitePlus | |||
T422 | Phosphorylation | score1 | PhosphoSitePlus | |||
T424 | Phosphorylation | score1 | PhosphoSitePlus | |||
K427 | Acetylation | score1 | PhosphoSitePlus | |||
T445 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 20953893 | ||
K446 | Ubiquitination | score1 | PhosphoSitePlus | |||
K456 | Sumoylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T66 | K66 | Biomuta | DOID:3571 / liver cancer [ icgc ] | |
S97 | N97 | Biomuta | DOID:4362 / cervical cancer [ tcga ] | |
S184 | Y184 | Biomuta | DOID:363 / uterine cancer [ cosmic, tcga ] DOID:1612 / breast cancer [ icgc, tcga ] DOID:11054 / urinary bladder cancer [ tcga ] | |
S249 | F249 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] | |
S384 | F384 | Biomuta | DOID:3070 / malignant glioma [ icgc ] | |
T392 | M392 | Biomuta | DOID:1324 / lung cancer [ tcga ] DOID:3070 / malignant glioma [ tcga ] | |
T424 | M424 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc, tcga ] | |
T424 | K424 | Biomuta | DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ] | |
T445 | N445 | Biomuta | DOID:3571 / liver cancer [ icgc ] |