iPTMnet Report for Q13118 (KLF10)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13118 / KLF10_HUMAN
Protein Name Krueppel-like factor 10
Gene Name Name: KLF10
Synonyms:TIEG,TIEG1;
Organism Homo sapiens (Human)

PRO ID PR:Q13118
DAG View
PRO Name krueppel-like factor 10 (human)
Definition A krueppel-like factor 10 that is encoded in the genome of human.
Short Label hKLF10
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13118 (KLF10) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K32 Ubiquitination PhosphoSitePlus
T66 Phosphorylation IEDB   PhosphoSitePlus 27869121
T93 Phosphorylation P04049 (RAF1) PhosphoSitePlus   RLIMS-P 23994618
S97 Phosphorylation PhosphoSitePlus
K135 Sumoylation PhosphoSitePlus
K139 Ubiquitination PhosphoSitePlus
S140 Phosphorylation PhosphoSitePlus
K149 Sumoylation PhosphoSitePlus
K149 Ubiquitination PhosphoSitePlus
S184 Phosphorylation PhosphoSitePlus   UniProt 23186163
S206 Phosphorylation P24941 (CDK2) PhosphoSitePlus   RLIMS-P+ 25728284
K223 Ubiquitination PhosphoSitePlus
C241 Methylation IEDB 31844290
S249 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 16964243
S351 Phosphorylation PhosphoSitePlus
K356 Ubiquitination PhosphoSitePlus
K378 Ubiquitination PhosphoSitePlus
S383 Phosphorylation PhosphoSitePlus
S384 Phosphorylation PhosphoSitePlus   RLIMS-P 20953893
K387 Ubiquitination PhosphoSitePlus
T392 Phosphorylation PhosphoSitePlus
T394 Phosphorylation PhosphoSitePlus
T422 Phosphorylation PhosphoSitePlus
T424 Phosphorylation PhosphoSitePlus
K427 Acetylation PhosphoSitePlus
T445 Phosphorylation PhosphoSitePlus   RLIMS-P 20953893
K446 Ubiquitination PhosphoSitePlus
K456 Sumoylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S249 Phosphorylation HPRD 18669648, 16964243
Site PTM Type PTM Enzyme Score Source PMID
S238 Phosphorylation HPRD 18669648, 16964243


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S97 N97 Biomuta DOID:4362 / cervical cancer [ icgc ]
S184 Y184 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S238 F238 Biomuta DOID:1612 / breast cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic, icgc ]
S249 F249 Biomuta DOID:1612 / breast cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic, icgc ]
S384 F384 Biomuta DOID:1319 / brain cancer [ icgc ]
T392 M392 Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
T424 M424 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T424 K424 Biomuta DOID:3571 / liver cancer [ cosmic ]