Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13112 / CAF1B_HUMAN
Protein Name Chromatin assembly factor 1 subunit B
Gene Name Name: CHAF1B
Synonyms:CAF1A,CAF1P60,MPHOSPH7,MPP7;
Organism Homo sapiens (Human)

PRO ID PR:Q13112
DAG View
PRO Name chromatin assembly factor 1 subunit B (human)
Definition A chromatin assembly factor 1 subunit B that is encoded in the genome of human.
Short Label hCHAF1B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13112 (CHAF1B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C6 Methylation IEDB 31844290
K13 Ubiquitination PhosphoSitePlus
S34 Phosphorylation PhosphoSitePlus
T39 Phosphorylation PhosphoSitePlus
K45 Ubiquitination PhosphoSitePlus
K53 Ubiquitination PhosphoSitePlus
S60 Phosphorylation PhosphoSitePlus
T66 Phosphorylation PhosphoSitePlus
K67 Ubiquitination PhosphoSitePlus
K99 Ubiquitination PhosphoSitePlus
K116 Ubiquitination PhosphoSitePlus
K123 Ubiquitination PhosphoSitePlus
K163 Ubiquitination PhosphoSitePlus
K202 Ubiquitination PhosphoSitePlus
K203 Ubiquitination PhosphoSitePlus
K211 Ubiquitination PhosphoSitePlus
K234 Ubiquitination PhosphoSitePlus
K275 Ubiquitination PhosphoSitePlus
C283 Methylation IEDB 31844290
K385 Ubiquitination PhosphoSitePlus
K387 Ubiquitination PhosphoSitePlus
T394 Phosphorylation PhosphoSitePlus   UniProt 23186163
T397 Phosphorylation PhosphoSitePlus
S403 Phosphorylation PhosphoSitePlus
R407 Methylation PhosphoSitePlus
S409 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17322306, 17081983, 19664995, ...18452278, 19651622, 18669648, 20068231
S410 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 19415658, 19664995
T419 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18220336, 19651622, ...18669648, 20068231
S422 Phosphorylation HPRD   PhosphoSitePlus 19651622, 17081983, 20068231
T424 Phosphorylation PhosphoSitePlus
S428 Phosphorylation HPRD   PhosphoSitePlus 19413330, 19664995
S429 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 23186163, 18220336, ...19664994, 15302935, 19664995, 19415658, 19651622, 18669648, 19690332, 20068231
T432 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19413330, 19664995, 19651622, ...18669648, 19415658, 20068231
T433 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 23186163, 19664995, ...19651622, 18669648, 20068230
T453 Phosphorylation PhosphoSitePlus
S458 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 21406692, 23186163, ...17081983, 18669648, 20068231
S464 Phosphorylation PhosphoSitePlus
S473 Phosphorylation HPRD   PhosphoSitePlus 20068231
K477 Ubiquitination PhosphoSitePlus
T485 Phosphorylation HPRD   PhosphoSitePlus 17924679
K494 Acetylation PhosphoSitePlus   UniProt 19608861
K494 Ubiquitination PhosphoSitePlus
T496 Phosphorylation PhosphoSitePlus
T503 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 20068231
T509 Phosphorylation phospho.ELM 18669648
S512 Phosphorylation HPRD   phospho.ELM 18669648
S520 Phosphorylation phospho.ELM 18669648
T524 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19413330, 18669648
S529 Phosphorylation HPRD   PhosphoSitePlus 19413330
T531 Phosphorylation PhosphoSitePlus
S538 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 18669648, 15302935
T554 Phosphorylation PhosphoSitePlus
S556 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K13 N13 Biomuta DOID:184 / bone cancer [ cosmic ]
K163 N163 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R407 * Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S410 L410 Biomuta DOID:4159 / skin cancer [ cosmic ]
T419 P419 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T419 I419 Biomuta [ cosmic ] DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
T432 M432 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S464 L464 Biomuta DOID:10283 / prostate cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ]
T531 M531 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]