iPTMnet Report for Q13085 (ACACA)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13085 / ACACA_HUMAN
Protein Name Acetyl-CoA carboxylase 1
Gene Name Name: ACACA
Synonyms:ACAC,ACC1,ACCA;
Organism Homo sapiens (Human)

PRO ID PR:Q13085
DAG View
PRO Name acetyl-CoA carboxylase 1 (human)
Definition An acetyl-CoA carboxylase 1 that is encoded in the genome of human.
Short Label hACACA
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13085 (ACACA) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19369195, 20068231
S5 Phosphorylation PhosphoSitePlus   UniProt 19369195, 23186163, 20068231
S23 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17081983, 15302935, 18669648, ...19690332, 20068231, 2900140
S25 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 15302935, ...18669648, 24275569, 19690332, 2900140
S29 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 21406692, 23186163, ...17081983, 19369195, 15302935, 18669648, 24275569, 19690332, 20068231, 2900140
S34 Phosphorylation PhosphoSitePlus
K45 Ubiquitination PhosphoSitePlus
S48 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17081983, 20068231
S50 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983, 18220336
S53 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17081983
S56 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
T58 Phosphorylation phospho.ELM 17081983
S60 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S77 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus 2900138, 15302935
S77 Phosphorylation P17612 (PRKACA) neXtProt 2900138
S78 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus 17519230, 7907095
S78 Phosphorylation P54646 (PRKAA2) neXtProt 17519230
S80 Phosphorylation phospho.ELM   PhosphoSitePlus   Signor   UniProt 2900138, 18303014, 23186163, ...26456332, 21406692, 12015362, 18669648, 17276402, 15371448, 11052978, 29899443, 19176702, 20068231
S80 Phosphorylation P54646 (PRKAA2) PhosphoSitePlus   Signor 12015362, 15371448
S80 Phosphorylation Q13131 (PRKAA1) PhosphoSitePlus 19176702, 18303014, 17276402, ...26456332
K86 Ubiquitination PhosphoSitePlus
S96 Phosphorylation PhosphoSitePlus
S104 Phosphorylation PhosphoSitePlus
K116 Ubiquitination PhosphoSitePlus
K120 Ubiquitination PhosphoSitePlus
K132 Ubiquitination PhosphoSitePlus
S234 Phosphorylation PhosphoSitePlus
K276 Ubiquitination PhosphoSitePlus
K288 Ubiquitination PhosphoSitePlus
Y290 Phosphorylation PhosphoSitePlus
K292 Ubiquitination PhosphoSitePlus
K311 Ubiquitination PhosphoSitePlus
S344 Phosphorylation PhosphoSitePlus
C378 Methylation IEDB 31844290
K386 Ubiquitination PhosphoSitePlus
K410 Ubiquitination PhosphoSitePlus
Y417 Phosphorylation PhosphoSitePlus
Y434 Phosphorylation PhosphoSitePlus
S488 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18220336
K520 Ubiquitination PhosphoSitePlus
K579 Ubiquitination PhosphoSitePlus
T610 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y676 Phosphorylation PhosphoSitePlus
Y734 Phosphorylation PhosphoSitePlus
K747 Ubiquitination PhosphoSitePlus
S756 Phosphorylation PhosphoSitePlus
K817 Ubiquitination PhosphoSitePlus
K825 Ubiquitination PhosphoSitePlus
S835 Phosphorylation PhosphoSitePlus   UniProt 23186163
S841 Phosphorylation PhosphoSitePlus
Y855 Phosphorylation PhosphoSitePlus
Y867 Phosphorylation PhosphoSitePlus
K879 Ubiquitination PhosphoSitePlus
S893 Phosphorylation PhosphoSitePlus
S907 Phosphorylation PhosphoSitePlus
K916 Ubiquitination PhosphoSitePlus
S977 Phosphorylation PhosphoSitePlus
Y994 Phosphorylation PhosphoSitePlus
T1042 Phosphorylation PhosphoSitePlus
T1073 Phosphorylation PhosphoSitePlus
K1076 Ubiquitination PhosphoSitePlus
T1196 Phosphorylation PhosphoSitePlus
S1201 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus 2900138, 7907095
S1201 Phosphorylation P17612 (PRKACA) neXtProt 2900138
Y1209 Phosphorylation PhosphoSitePlus
S1216 Phosphorylation PhosphoSitePlus
S1218 Phosphorylation PhosphoSitePlus
T1227 Phosphorylation PhosphoSitePlus
C1230 Methylation IEDB 31844290
C1255 Methylation IEDB 31844290
S1257 Phosphorylation PhosphoSitePlus
S1259 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1263 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 19061860, 17081983, 16698035, ...18669648, 29899443
T1265 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1273 Phosphorylation PhosphoSitePlus   UniProt 24275569
K1316 Ubiquitination PhosphoSitePlus
K1334 Acetylation PhosphoSitePlus   UniProt 19608861
K1334 Ubiquitination PhosphoSitePlus
K1338 Ubiquitination PhosphoSitePlus
Y1342 Phosphorylation PhosphoSitePlus
K1354 Ubiquitination PhosphoSitePlus
Y1370 Phosphorylation PhosphoSitePlus
K1435 Ubiquitination PhosphoSitePlus
S1438 Phosphorylation PhosphoSitePlus
Y1441 Phosphorylation PhosphoSitePlus
Y1499 Phosphorylation PhosphoSitePlus
K1524 Ubiquitination PhosphoSitePlus
K1580 Acetylation PhosphoSitePlus
K1586 Ubiquitination PhosphoSitePlus
S1720 Phosphorylation PhosphoSitePlus
Y1745 Phosphorylation PhosphoSitePlus
K1759 Acetylation PhosphoSitePlus
K1759 Ubiquitination PhosphoSitePlus
K1781 Ubiquitination PhosphoSitePlus
K1788 Acetylation PhosphoSitePlus
K1788 Ubiquitination PhosphoSitePlus
S1844 Phosphorylation PhosphoSitePlus
K1856 Acetylation PhosphoSitePlus
K1856 Ubiquitination PhosphoSitePlus
S1908 Phosphorylation PhosphoSitePlus
K1916 Ubiquitination PhosphoSitePlus
K1929 Ubiquitination PhosphoSitePlus
K2031 Acetylation PhosphoSitePlus
K2031 Ubiquitination PhosphoSitePlus
R2047 Methylation PhosphoSitePlus
S2099 Phosphorylation PhosphoSitePlus
Y2108 Phosphorylation PhosphoSitePlus
K2127 Acetylation PhosphoSitePlus
K2127 Ubiquitination PhosphoSitePlus
K2135 Ubiquitination PhosphoSitePlus
Y2144 Phosphorylation PhosphoSitePlus
T2153 Phosphorylation PhosphoSitePlus   UniProt 23186163
K2209 Ubiquitination PhosphoSitePlus
K2231 Ubiquitination PhosphoSitePlus
K2268 Ubiquitination PhosphoSitePlus
K2293 Ubiquitination PhosphoSitePlus
C2294 Methylation IEDB 31844290
K2302 Ubiquitination PhosphoSitePlus
S2318 Phosphorylation PhosphoSitePlus
S2343 Phosphorylation PhosphoSitePlus
S2345 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S5 Phosphorylation HPRD 18691976, 20068231
S23 Phosphorylation HPRD 18669648, 19415658, 20068231, ...2900140
S25 Phosphorylation HPRD 20166139, 18691976, 18669648, ...20068231, 2900140
S29 Phosphorylation HPRD 19413330, 18691976, 18212344, ...18767875, 19664994, 19664995, 18452278, 19651622, 18669648, 20166139, 19415658, 20068231, 2900140
S29 Phosphorylation P19784 (CSNK2A2) HPRD 19413330, 18691976, 18212344, ...18767875, 19664994, 19664995, 18452278, 19651622, 18669648, 20166139, 19415658, 20068231, 2900140
S29 Phosphorylation P68400 (CSNK2A1) HPRD 19413330, 18691976, 18212344, ...18767875, 19664994, 19664995, 18452278, 19651622, 18669648, 20166139, 19415658, 20068231, 2900140
S48 Phosphorylation HPRD 18691976, 17081983, 20068231
S50 Phosphorylation HPRD 17081983, 20068231
S53 Phosphorylation HPRD 17081983
S56 Phosphorylation HPRD 17081983
T58 Phosphorylation HPRD 17081983
S60 Phosphorylation HPRD 17081983
S78 Phosphorylation HPRD 7907095
S80 Phosphorylation HPRD 2900138, 18212344, 18767875, ...19651622, 18669648, 18707149, 20166139, 7907095, 20068231
S80 Phosphorylation P54646 (PRKAA2) HPRD 2900138, 18212344, 18767875, ...19651622, 18669648, 18707149, 20166139, 7907095, 20068231
S80 Phosphorylation Q13131 (PRKAA1) HPRD 2900138, 18212344, 18767875, ...19651622, 18669648, 18707149, 20166139, 7907095, 20068231
T1042 Phosphorylation HPRD 17287340, 20068231
S1201 Phosphorylation HPRD 2900138, 7907095
S1201 Phosphorylation Q13131 (PRKAA1) HPRD 2900138, 7907095
S1216 Phosphorylation HPRD 7915280
S1257 Phosphorylation HPRD 17081983
S1259 Phosphorylation HPRD 18669648, 17081983
S1263 Phosphorylation HPRD 18669648
T1265 Phosphorylation HPRD 18669648
S1438 Phosphorylation HPRD 20068231
Y1441 Phosphorylation HPRD 20068231
S2099 Phosphorylation HPRD 17287340
Y2108 Phosphorylation HPRD 17287340
S2343 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S20 Phosphorylation HPRD 7907095
S22 Phosphorylation HPRD 2900138, 18212344, 18767875, ...19651622, 18669648, 18707149, 20166139, 11052978, 20068231
S22 Phosphorylation P54646 (PRKAA2) HPRD 2900138, 18212344, 18767875, ...19651622, 18669648, 18707149, 20166139, 11052978, 20068231
S22 Phosphorylation Q13131 (PRKAA1) HPRD 2900138, 18212344, 18767875, ...19651622, 18669648, 18707149, 20166139, 11052978, 20068231
T984 Phosphorylation HPRD 17287340, 20068231
S1143 Phosphorylation HPRD 2900138, 7907095
S1158 Phosphorylation HPRD 7915280
S1199 Phosphorylation HPRD 17081983
S1201 Phosphorylation HPRD 18669648, 17081983
S1205 Phosphorylation HPRD 18669648
T1207 Phosphorylation HPRD 18669648
S1380 Phosphorylation HPRD 20068231
Y1383 Phosphorylation HPRD 20068231
S2041 Phosphorylation HPRD 17287340
Y2050 Phosphorylation HPRD 17287340
S2285 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
T964 Phosphorylation HPRD 17287340, 20068231
S1123 Phosphorylation HPRD 2900138, 7907095
S1138 Phosphorylation HPRD 7915280
S1179 Phosphorylation HPRD 17081983
S1181 Phosphorylation HPRD 18669648, 17081983
S1185 Phosphorylation HPRD 18669648
T1187 Phosphorylation HPRD 18669648
S1360 Phosphorylation HPRD 20068231
Y1363 Phosphorylation HPRD 20068231
S2021 Phosphorylation HPRD 17287340
Y2030 Phosphorylation HPRD 17287340
S2265 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation PhosphoSitePlus
T5 Phosphorylation PhosphoSitePlus
S8 Phosphorylation PhosphoSitePlus
S42 Phosphorylation HPRD 18691976, 20068231
S60 Phosphorylation HPRD 18669648, 19415658, 20068231, ...2900140
S62 Phosphorylation HPRD 20166139, 18691976, 18669648, ...20068231, 2900140
S66 Phosphorylation HPRD 19413330, 18691976, 18212344, ...18767875, 19664994, 19664995, 18452278, 19651622, 18669648, 20166139, 19415658, 20068231, 2900140
S66 Phosphorylation P19784 (CSNK2A2) HPRD 19413330, 18691976, 18212344, ...18767875, 19664994, 19664995, 18452278, 19651622, 18669648, 20166139, 19415658, 20068231, 2900140
S66 Phosphorylation P68400 (CSNK2A1) HPRD 19413330, 18691976, 18212344, ...18767875, 19664994, 19664995, 18452278, 19651622, 18669648, 20166139, 19415658, 20068231, 2900140
S85 Phosphorylation HPRD 18691976, 17081983, 20068231
S87 Phosphorylation HPRD 17081983, 20068231
S90 Phosphorylation HPRD 17081983
S93 Phosphorylation HPRD 17081983
T95 Phosphorylation HPRD 17081983
S97 Phosphorylation HPRD 17081983
S115 Phosphorylation HPRD 7907095
S117 Phosphorylation HPRD 2900138, 18212344, 18767875, ...19651622, 18669648, 18707149, 20166139, 11052978, 20068231
S117 Phosphorylation P54646 (PRKAA2) HPRD 2900138, 18212344, 18767875, ...19651622, 18669648, 18707149, 20166139, 11052978, 20068231
S117 Phosphorylation Q13131 (PRKAA1) HPRD 2900138, 18212344, 18767875, ...19651622, 18669648, 18707149, 20166139, 11052978, 20068231
T1079 Phosphorylation HPRD 17287340, 20068231
S1238 Phosphorylation HPRD 2900138, 7907095
S1238 Phosphorylation Q13131 (PRKAA1) HPRD 2900138, 7907095
S1253 Phosphorylation HPRD 7915280
S1294 Phosphorylation HPRD 17081983
S1296 Phosphorylation HPRD 18669648, 17081983
S1300 Phosphorylation HPRD 18669648
T1302 Phosphorylation HPRD 18669648
S1475 Phosphorylation HPRD 20068231
Y1478 Phosphorylation HPRD 20068231
S2136 Phosphorylation HPRD 17287340
Y2145 Phosphorylation HPRD 17287340
S2380 Phosphorylation HPRD 20068231