iPTMnet Report for Q13029 (PRDM2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13029 / PRDM2_HUMAN
Protein Name PR domain zinc finger protein 2
Gene Name Name: PRDM2
Synonyms:KMT8,RIZ;
Organism Homo sapiens (Human)

PRO ID PR:Q13029
DAG View
PRO Name PR domain zinc finger protein 2 (human)
Definition A PR domain zinc finger protein 2 that is encoded in the genome of human.
Short Label hPRDM2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13029 (PRDM2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T47 Phosphorylation PhosphoSitePlus
K63 Ubiquitination PhosphoSitePlus
T198 Phosphorylation PhosphoSitePlus
S199 Phosphorylation PhosphoSitePlus
S421 Phosphorylation PhosphoSitePlus   UniProt 23186163
T423 Phosphorylation PhosphoSitePlus
S427 Phosphorylation PhosphoSitePlus
S447 Phosphorylation PhosphoSitePlus
S471 Phosphorylation PhosphoSitePlus
R508 Methylation PhosphoSitePlus
R516 Methylation PhosphoSitePlus
K626 Ubiquitination PhosphoSitePlus
T641 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S643 Phosphorylation IEDB   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 15302935, 17081983, ...27869121
K700 Ubiquitination PhosphoSitePlus
T702 Phosphorylation PhosphoSitePlus
S720 Phosphorylation PhosphoSitePlus
T737 Phosphorylation PhosphoSitePlus
S738 Phosphorylation PhosphoSitePlus
S739 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
S742 Phosphorylation PhosphoSitePlus
S743 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18220336
S747 Phosphorylation PhosphoSitePlus
K774 Ubiquitination PhosphoSitePlus
S781 Phosphorylation PhosphoSitePlus
S785 Phosphorylation PhosphoSitePlus
S796 Phosphorylation PhosphoSitePlus   UniProt 23186163
S846 Phosphorylation PhosphoSitePlus
S876 Phosphorylation PhosphoSitePlus
T885 Phosphorylation PhosphoSitePlus
Y896 Phosphorylation PhosphoSitePlus
T910 Phosphorylation PhosphoSitePlus
S912 Phosphorylation PhosphoSitePlus
S914 Phosphorylation PhosphoSitePlus
S1054 Phosphorylation PhosphoSitePlus
S1055 Phosphorylation PhosphoSitePlus
S1056 Phosphorylation PhosphoSitePlus
S1057 Phosphorylation PhosphoSitePlus
S1118 Phosphorylation PhosphoSitePlus
S1141 Phosphorylation PhosphoSitePlus
C1164 Methylation IEDB 31844290
T1255 Phosphorylation phospho.ELM 18669648
S1256 Phosphorylation PhosphoSitePlus
S1265 Phosphorylation PhosphoSitePlus
S1266 Phosphorylation phospho.ELM 18669648
Y1295 Phosphorylation PhosphoSitePlus
S1297 Phosphorylation PhosphoSitePlus
S1359 Phosphorylation PhosphoSitePlus
S1414 Phosphorylation PhosphoSitePlus
K1425 Acetylation PhosphoSitePlus
K1431 Acetylation PhosphoSitePlus
S1484 Phosphorylation PhosphoSitePlus
S1491 Phosphorylation PhosphoSitePlus
S1509 Phosphorylation PhosphoSitePlus
S1511 Phosphorylation PhosphoSitePlus
T1517 O-Glycosylation GlyGen 30379171, 30620550
T1529 Phosphorylation PhosphoSitePlus
S1571 Phosphorylation PhosphoSitePlus
T1585 Phosphorylation PhosphoSitePlus
K1597 Ubiquitination PhosphoSitePlus
K1606 Ubiquitination PhosphoSitePlus
S1626 O-Glycosylation GlyGen 30379171, 30620550
S1641 Phosphorylation PhosphoSitePlus
S1645 Phosphorylation PhosphoSitePlus
S1652 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T641 Phosphorylation HPRD 20058876, 17081983
S643 Phosphorylation HPRD 15302935, 20058876
T737 Phosphorylation HPRD 19651622
S738 Phosphorylation HPRD 17081983
S739 Phosphorylation HPRD 17081983
S743 Phosphorylation HPRD 19651622, 17081983
S747 Phosphorylation HPRD 17081983
T1255 Phosphorylation HPRD 18669648
S1266 Phosphorylation HPRD 18669648
Site PTM Type PTM Enzyme Score Source PMID
T641 Phosphorylation HPRD 20058876, 17081983
S643 Phosphorylation HPRD 15302935, 20058876
T737 Phosphorylation HPRD 19651622
S738 Phosphorylation HPRD 17081983
S739 Phosphorylation HPRD 17081983
S743 Phosphorylation HPRD 19651622, 17081983
S747 Phosphorylation HPRD 17081983
T1255 Phosphorylation HPRD 18669648
S1266 Phosphorylation HPRD 18669648
K1676 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S174 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T440 Phosphorylation HPRD 20058876, 17081983
S442 Phosphorylation HPRD 15302935, 20058876
T536 Phosphorylation HPRD 19651622
S537 Phosphorylation HPRD 17081983
S538 Phosphorylation HPRD 17081983
S542 Phosphorylation HPRD 19651622, 17081983
S546 Phosphorylation HPRD 17081983
T1054 Phosphorylation HPRD 18669648
S1065 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S199 Y199 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R516 W516 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R516 Q516 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
T536 I536 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S542 F542 Biomuta DOID:1612 / breast cancer [ cosmic ]
S546 I546 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T702 P702 Biomuta DOID:4159 / skin cancer [ cosmic ]
S720 Y720 Biomuta DOID:363 / uterine cancer [ icgc ]
S720 P720 Biomuta DOID:3571 / liver cancer [ cosmic ]
T737 I737 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S743 F743 Biomuta DOID:1612 / breast cancer [ cosmic ]
S747 I747 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K774 T774 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S796 I796 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S846 C846 Biomuta DOID:4159 / skin cancer [ cosmic ]
S876 G876 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S914 R914 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T1054 A1054 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T1255 A1255 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S1256 Y1256 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1297 C1297 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S1297 R1297 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1414 W1414 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
S1414 L1414 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T1529 S1529 Biomuta DOID:3571 / liver cancer [ cosmic ]
S1641 Y1641 Biomuta DOID:9256 / colorectal cancer [ cosmic ]