iPTMnet Report for Q13023 (AKAP6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13023 / AKAP6_HUMAN
Protein Name A-kinase anchor protein 6
Gene Name Name: AKAP6
Synonyms:AKAP100,KIAA0311;
Organism Homo sapiens (Human)

PRO ID PR:Q13023
DAG View
PRO Name A-kinase anchor protein 6 (human)
Definition An A-kinase anchor protein 6 that is encoded in the genome of human.
Short Label hAKAP6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13023 (AKAP6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K370 Acetylation PhosphoSitePlus
S422 Phosphorylation PhosphoSitePlus
S455 Phosphorylation PhosphoSitePlus
S481 Phosphorylation PhosphoSitePlus
S574 O-Glycosylation GlyGen 30379171, 28411811, 31492838, ...29351928
K604 Methylation PhosphoSitePlus
T651 Phosphorylation PhosphoSitePlus
K931 Ubiquitination PhosphoSitePlus
Y1002 Phosphorylation PhosphoSitePlus
S1003 Phosphorylation PhosphoSitePlus
S1007 Phosphorylation PhosphoSitePlus
T1051 Phosphorylation PhosphoSitePlus
T1059 Phosphorylation PhosphoSitePlus
S1067 Phosphorylation PhosphoSitePlus
S1073 Phosphorylation PhosphoSitePlus
S1076 Phosphorylation PhosphoSitePlus
S1325 Phosphorylation PhosphoSitePlus
T1333 Phosphorylation PhosphoSitePlus
S1335 Phosphorylation PhosphoSitePlus
Y1472 Phosphorylation PhosphoSitePlus
S1533 Phosphorylation PhosphoSitePlus
S1540 Phosphorylation PhosphoSitePlus
S1595 Phosphorylation PhosphoSitePlus
S1644 Phosphorylation PhosphoSitePlus
S1655 Phosphorylation PhosphoSitePlus
T1837 Phosphorylation phospho.ELM 18669648
S1840 Phosphorylation phospho.ELM 18669648
S1857 Phosphorylation PhosphoSitePlus
S1867 Phosphorylation PhosphoSitePlus
S1941 Phosphorylation PhosphoSitePlus
S1999 Phosphorylation PhosphoSitePlus
S2068 O-Glycosylation GlyGen 30379171, 28411811, 31492838, ...29351928
T2069 O-Glycosylation GlyGen 30379171, 28411811, 31492838, ...29351928
S2255 Phosphorylation PhosphoSitePlus
S2256 Phosphorylation PhosphoSitePlus
S2262 Phosphorylation PhosphoSitePlus
K2276 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T1837 Phosphorylation HPRD 18669648
S1840 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S455 T455 Biomuta DOID:4159 / skin cancer [ icgc ]
S574 R574 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T651 A651 Biomuta DOID:363 / uterine cancer [ icgc ]
K931 T931 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
Y1002 C1002 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S1073 F1073 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1325 C1325 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1335 Y1335 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y1472 S1472 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1540 L1540 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1595 F1595 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1655 F1655 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ]
T1837 I1837 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S1999 C1999 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S2068 L2068 Biomuta [ cosmic ] DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
K2276 E2276 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
K2276 N2276 Biomuta DOID:9256 / colorectal cancer [ cosmic ]