iPTMnet Report for Q12986 (NFX1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q12986 / NFX1_HUMAN
Protein Name Transcriptional repressor NF-X1
Gene Name Name: NFX1
Synonyms:NFX2;
Organism Homo sapiens (Human)

PRO ID PR:Q12986
DAG View
PRO Name transcriptional repressor NF-X1 (human)
Definition A transcriptional repressor NF-X1 that is encoded in the genome of human.
Short Label hNFX1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q12986 (NFX1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S8 Phosphorylation PhosphoSitePlus
K25 Ubiquitination PhosphoSitePlus
S49 Phosphorylation PhosphoSitePlus
S50 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163
S86 Phosphorylation PhosphoSitePlus
S90 Phosphorylation PhosphoSitePlus
S95 Phosphorylation PhosphoSitePlus   UniProt 23186163
K97 Ubiquitination PhosphoSitePlus
K108 Ubiquitination PhosphoSitePlus
K120 Ubiquitination PhosphoSitePlus
S123 Phosphorylation PhosphoSitePlus
S142 Phosphorylation PhosphoSitePlus
S150 Phosphorylation PhosphoSitePlus   UniProt 23186163
S152 Phosphorylation PhosphoSitePlus
S154 Phosphorylation PhosphoSitePlus
T172 Phosphorylation PhosphoSitePlus
Y176 Phosphorylation PhosphoSitePlus
S177 Phosphorylation PhosphoSitePlus
S193 Phosphorylation IEDB   PhosphoSitePlus 35494241
K199 Ubiquitination PhosphoSitePlus
K209 Ubiquitination PhosphoSitePlus
K225 Ubiquitination PhosphoSitePlus
Y231 Phosphorylation PhosphoSitePlus
K283 Ubiquitination PhosphoSitePlus
K292 Methylation PhosphoSitePlus
K305 Ubiquitination PhosphoSitePlus
K314 Ubiquitination PhosphoSitePlus
S326 Phosphorylation PhosphoSitePlus   UniProt 23186163
S329 Phosphorylation PhosphoSitePlus
S346 Phosphorylation PhosphoSitePlus
S392 Phosphorylation PhosphoSitePlus
C421 Methylation IEDB 31844290
K427 Ubiquitination PhosphoSitePlus
K548 Ubiquitination PhosphoSitePlus
K559 Ubiquitination PhosphoSitePlus
T599 Phosphorylation PhosphoSitePlus
S602 Phosphorylation PhosphoSitePlus
S609 Phosphorylation PhosphoSitePlus
K613 Ubiquitination PhosphoSitePlus
K628 Ubiquitination PhosphoSitePlus
S634 Phosphorylation PhosphoSitePlus
K668 Ubiquitination PhosphoSitePlus
S677 Phosphorylation PhosphoSitePlus
T681 Phosphorylation PhosphoSitePlus
K686 Ubiquitination PhosphoSitePlus
K690 Ubiquitination PhosphoSitePlus
K691 Ubiquitination PhosphoSitePlus
K710 Ubiquitination PhosphoSitePlus
Y783 Phosphorylation PhosphoSitePlus
S788 Phosphorylation PhosphoSitePlus
K885 Ubiquitination PhosphoSitePlus
T907 Phosphorylation PhosphoSitePlus
S967 Phosphorylation PhosphoSitePlus
S978 Phosphorylation PhosphoSitePlus
S980 Phosphorylation PhosphoSitePlus
K981 Acetylation PhosphoSitePlus
K981 Ubiquitination PhosphoSitePlus
S985 Phosphorylation PhosphoSitePlus
K995 Ubiquitination PhosphoSitePlus
K1013 Ubiquitination PhosphoSitePlus
Y1041 Phosphorylation PhosphoSitePlus
S1095 Phosphorylation PhosphoSitePlus
K1097 Ubiquitination PhosphoSitePlus
K1106 Ubiquitination PhosphoSitePlus
Y1115 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S49 Phosphorylation HPRD 17081983, 20068231
S50 Phosphorylation HPRD 18669648, 20068231
S90 Phosphorylation HPRD 19413330
T144 Phosphorylation HPRD 17081983
S326 Phosphorylation HPRD 19651622, 19664994, 20068231
Site PTM Type PTM Enzyme Score Source PMID
T34 Phosphorylation PhosphoSitePlus
Y48 Phosphorylation PhosphoSitePlus
S49 Phosphorylation PhosphoSitePlus
S50 Phosphorylation PhosphoSitePlus
Y176 Phosphorylation PhosphoSitePlus
S177 Phosphorylation PhosphoSitePlus
Y178 Phosphorylation PhosphoSitePlus
Y231 Phosphorylation PhosphoSitePlus
T316 Phosphorylation PhosphoSitePlus
S664 Phosphorylation PhosphoSitePlus
K791 Ubiquitination PhosphoSitePlus
K981 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T34 Phosphorylation PhosphoSitePlus
Y48 Phosphorylation PhosphoSitePlus
S49 Phosphorylation HPRD   PhosphoSitePlus 17081983, 20068231
S50 Phosphorylation HPRD   PhosphoSitePlus 18669648, 20068231
S90 Phosphorylation HPRD 19413330
T144 Phosphorylation HPRD 17081983
Y176 Phosphorylation PhosphoSitePlus
S177 Phosphorylation PhosphoSitePlus
Y178 Phosphorylation PhosphoSitePlus
Y231 Phosphorylation PhosphoSitePlus
T316 Phosphorylation PhosphoSitePlus
S326 Phosphorylation HPRD 19651622, 19664994, 20068231
K791 Ubiquitination PhosphoSitePlus
Y812 Phosphorylation PhosphoSitePlus
K818 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S49 I49 Biomuta DOID:3571 / liver cancer [ cosmic ]
S95 L95 Biomuta DOID:1319 / brain cancer [ icgc ] DOID:3571 / liver cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
K314 T314 Biomuta DOID:363 / uterine cancer [ icgc ]
K613 * Biomuta DOID:1324 / lung cancer [ cosmic ]
K710 N710 Biomuta DOID:2531 / hematologic cancer [ cosmic ]