iPTMnet Report for Q12980 (NPRL3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q12980 / NPRL3_HUMAN
Protein Name GATOR1 complex protein NPRL3
Gene Name Name: NPRL3
Synonyms:C16orf35;
Organism Homo sapiens (Human)

PRO ID PR:Q12980
DAG View
PRO Name GATOR complex protein NPRL3 (human)
Definition A GATOR complex protein NPRL3 that is encoded in the genome of human.
Short Label hNPRL3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q12980 (NPRL3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K21 Ubiquitination PhosphoSitePlus
K41 Ubiquitination PhosphoSitePlus
T51 Phosphorylation PhosphoSitePlus
S62 Phosphorylation PhosphoSitePlus
K76 Ubiquitination PhosphoSitePlus
K83 Ubiquitination PhosphoSitePlus
K87 Ubiquitination PhosphoSitePlus
K109 Ubiquitination PhosphoSitePlus
T120 Phosphorylation PhosphoSitePlus
C141 Methylation IEDB 31844290
C160 Methylation IEDB 31844290
S189 Phosphorylation PhosphoSitePlus
K205 Ubiquitination PhosphoSitePlus
Y208 Phosphorylation HPRD 20068231
K253 Ubiquitination PhosphoSitePlus
C278 Methylation IEDB 31844290
K287 Ubiquitination PhosphoSitePlus
C329 Methylation IEDB 31844290
N465 N-Glycosylation GlyGen 29671580
S476 Phosphorylation PhosphoSitePlus   UniProt 24275569
K546 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
N465 N-Glycosylation PRO 29671580


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T51 M51 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T120 I120 Biomuta DOID:4159 / skin cancer [ cosmic ]
C141 * Biomuta DOID:2531 / hematologic cancer [ cosmic ]
C329 W329 Biomuta DOID:3571 / liver cancer [ cosmic ]