iPTMnet Report for Q12979 (ABR)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q12979 / ABR_HUMAN
Protein Name Active breakpoint cluster region-related protein
Gene Name Name: ABR
Organism Homo sapiens (Human)

PRO ID PR:Q12979
DAG View
PRO Name active breakpoint cluster region-related protein (human)
Definition An active breakpoint cluster region-related protein that is encoded in the genome of human.
Short Label hABR
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q12979 (ABR) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R7 Methylation PhosphoSitePlus
S53 Phosphorylation PhosphoSitePlus
T55 Phosphorylation PhosphoSitePlus
S57 Phosphorylation PhosphoSitePlus
S72 Phosphorylation PhosphoSitePlus
K87 Ubiquitination PhosphoSitePlus
K151 Ubiquitination PhosphoSitePlus
K160 Ubiquitination PhosphoSitePlus
T169 Phosphorylation PhosphoSitePlus
K176 Ubiquitination PhosphoSitePlus
K185 Ubiquitination PhosphoSitePlus
K192 Ubiquitination PhosphoSitePlus
K200 Ubiquitination PhosphoSitePlus
K210 Ubiquitination PhosphoSitePlus
K216 Ubiquitination PhosphoSitePlus
K238 Ubiquitination PhosphoSitePlus
T244 Phosphorylation PhosphoSitePlus
S246 Phosphorylation PhosphoSitePlus
T247 Phosphorylation PhosphoSitePlus
Y264 Phosphorylation PhosphoSitePlus
K296 Ubiquitination PhosphoSitePlus
T299 Phosphorylation PhosphoSitePlus
S366 Phosphorylation PhosphoSitePlus
K383 Ubiquitination PhosphoSitePlus
K388 Ubiquitination PhosphoSitePlus
K581 Ubiquitination PhosphoSitePlus
K589 Ubiquitination PhosphoSitePlus
K593 Ubiquitination PhosphoSitePlus
K606 Ubiquitination PhosphoSitePlus
S632 Phosphorylation PhosphoSitePlus
T636 Phosphorylation PhosphoSitePlus
S638 Phosphorylation PhosphoSitePlus
K640 Ubiquitination PhosphoSitePlus
T642 Phosphorylation PhosphoSitePlus
S650 Phosphorylation PhosphoSitePlus
K654 Ubiquitination PhosphoSitePlus
K659 Ubiquitination PhosphoSitePlus
Y662 Phosphorylation PhosphoSitePlus
K785 Acetylation PhosphoSitePlus
K785 Ubiquitination PhosphoSitePlus
K790 Ubiquitination PhosphoSitePlus
Y854 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T30 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S53 L53 Biomuta [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
T55 I55 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]
K210 R210 Biomuta DOID:263 / kidney cancer [ cosmic ]
S246 N246 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T299 M299 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S366 I366 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
K383 Q383 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K388 R388 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K388 N388 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
K581 T581 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S632 C632 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K659 Q659 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]