Protein Information

Cytoscape View


UniProt AC / UniProt ID Q12955 / ANK3_HUMAN
Protein Name Ankyrin-3
Gene Name Name: ANK3
Organism Homo sapiens (Human)

PRO ID PR:Q12955
DAG View
PRO Name ankyrin-3 (human)
Definition An ankyrin-3 that is encoded in the genome of human.
Short Label hANK3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q12955 (ANK3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K9 Acetylation PhosphoSitePlus
S39 Phosphorylation PhosphoSitePlus   UniProt 21406692
S44 Phosphorylation PhosphoSitePlus
Y60 Phosphorylation PhosphoSitePlus
Y245 Phosphorylation PhosphoSitePlus
K409 Acetylation PhosphoSitePlus
Y484 Phosphorylation PhosphoSitePlus
T501 Phosphorylation PhosphoSitePlus
S524 Phosphorylation PhosphoSitePlus
T529 Phosphorylation PhosphoSitePlus
T530 Phosphorylation PhosphoSitePlus
S531 Phosphorylation PhosphoSitePlus
Y533 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
T534 Phosphorylation PhosphoSitePlus
S539 Phosphorylation PhosphoSitePlus
Y575 Phosphorylation PhosphoSitePlus
S623 Phosphorylation PhosphoSitePlus
Y632 Phosphorylation PhosphoSitePlus
Y653 Phosphorylation PhosphoSitePlus
Y731 Phosphorylation PhosphoSitePlus
T732 Phosphorylation PhosphoSitePlus
Y740 Phosphorylation PhosphoSitePlus
Y808 Phosphorylation PhosphoSitePlus
S810 Phosphorylation PhosphoSitePlus
T814 Phosphorylation PhosphoSitePlus
T819 Phosphorylation PhosphoSitePlus
T822 Phosphorylation PhosphoSitePlus
S847 Phosphorylation PhosphoSitePlus   UniProt 21406692
S861 Phosphorylation PhosphoSitePlus
S867 Phosphorylation PhosphoSitePlus
Y883 Phosphorylation PhosphoSitePlus
S896 Phosphorylation PhosphoSitePlus
Y902 Phosphorylation PhosphoSitePlus
S906 Phosphorylation PhosphoSitePlus
S913 Phosphorylation PhosphoSitePlus
S916 Phosphorylation PhosphoSitePlus
S918 Phosphorylation PhosphoSitePlus
S919 Phosphorylation PhosphoSitePlus
R921 Methylation PhosphoSitePlus
S922 Phosphorylation PhosphoSitePlus
S934 Phosphorylation PhosphoSitePlus
S957 Phosphorylation PhosphoSitePlus
S959 Phosphorylation PhosphoSitePlus
S964 Phosphorylation PhosphoSitePlus
S1113 Phosphorylation PhosphoSitePlus
K1128 Acetylation PhosphoSitePlus
Y1366 Phosphorylation PhosphoSitePlus
T1404 Phosphorylation PhosphoSitePlus
S1405 Phosphorylation PhosphoSitePlus
S1445 Phosphorylation PhosphoSitePlus   UniProt 21406692
T1454 Phosphorylation PhosphoSitePlus
S1459 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1462 Phosphorylation PhosphoSitePlus
S1470 Phosphorylation PhosphoSitePlus
S1551 Phosphorylation PhosphoSitePlus
T1552 Phosphorylation PhosphoSitePlus
S1556 Phosphorylation PhosphoSitePlus
S1559 Phosphorylation PhosphoSitePlus
S1560 Phosphorylation PhosphoSitePlus
S1573 Phosphorylation PhosphoSitePlus
T1624 O-Glycosylation PhosphoSitePlus
S1625 O-Glycosylation PhosphoSitePlus
T1628 O-Glycosylation PhosphoSitePlus
T1629 O-Glycosylation PhosphoSitePlus
S1632 O-Glycosylation PhosphoSitePlus
T1642 Phosphorylation PhosphoSitePlus
S1646 Phosphorylation PhosphoSitePlus
Y1654 Phosphorylation PhosphoSitePlus
S1666 Phosphorylation PhosphoSitePlus
S1684 Phosphorylation PhosphoSitePlus
S1690 Phosphorylation PhosphoSitePlus
S1691 Phosphorylation PhosphoSitePlus
T1695 Phosphorylation PhosphoSitePlus
S1698 Phosphorylation PhosphoSitePlus
S1702 Phosphorylation PhosphoSitePlus
K1838 Acetylation PhosphoSitePlus
K1847 Acetylation PhosphoSitePlus
K1857 Acetylation PhosphoSitePlus
T1860 Phosphorylation PhosphoSitePlus
K1971 Ubiquitination PhosphoSitePlus
K1975 Ubiquitination PhosphoSitePlus
S1976 Phosphorylation PhosphoSitePlus
S1979 Phosphorylation PhosphoSitePlus
K2058 Acetylation PhosphoSitePlus
K2065 Acetylation PhosphoSitePlus
S2085 Phosphorylation PhosphoSitePlus
S2089 Phosphorylation PhosphoSitePlus
S2146 Phosphorylation PhosphoSitePlus
T2147 Phosphorylation PhosphoSitePlus
T2244 Phosphorylation PhosphoSitePlus
T2248 Phosphorylation PhosphoSitePlus
T2250 Phosphorylation PhosphoSitePlus
S2272 Phosphorylation PhosphoSitePlus
S2417 Phosphorylation PhosphoSitePlus
S2523 Phosphorylation PhosphoSitePlus
Y2544 Phosphorylation PhosphoSitePlus
S2592 Phosphorylation PhosphoSitePlus
T2599 Phosphorylation PhosphoSitePlus
S2608 Phosphorylation PhosphoSitePlus
S2668 Phosphorylation PhosphoSitePlus
S2672 Phosphorylation PhosphoSitePlus
S2694 Phosphorylation PhosphoSitePlus
S2696 Phosphorylation PhosphoSitePlus
S2698 Phosphorylation PhosphoSitePlus
S2716 Phosphorylation PhosphoSitePlus
S2717 Phosphorylation PhosphoSitePlus
K2739 Ubiquitination PhosphoSitePlus
K2749 Ubiquitination PhosphoSitePlus
S2858 Phosphorylation PhosphoSitePlus
S2991 Phosphorylation PhosphoSitePlus
S2997 Phosphorylation PhosphoSitePlus
S3000 Phosphorylation PhosphoSitePlus
T3091 Phosphorylation PhosphoSitePlus
Y3095 Phosphorylation PhosphoSitePlus
Y3133 Phosphorylation PhosphoSitePlus
S3157 Phosphorylation PhosphoSitePlus
S3162 Phosphorylation PhosphoSitePlus
T3168 Phosphorylation PhosphoSitePlus
Y3179 Phosphorylation PhosphoSitePlus
T3185 Phosphorylation PhosphoSitePlus
S3188 Phosphorylation PhosphoSitePlus
S3215 Phosphorylation PhosphoSitePlus
T3221 Phosphorylation PhosphoSitePlus
T3222 Phosphorylation PhosphoSitePlus
T3226 Phosphorylation PhosphoSitePlus
Y3324 Phosphorylation PhosphoSitePlus
K3472 Acetylation PhosphoSitePlus
S3513 Phosphorylation PhosphoSitePlus
S3620 Phosphorylation PhosphoSitePlus
T3709 Phosphorylation PhosphoSitePlus
T3711 Phosphorylation PhosphoSitePlus
S3712 Phosphorylation PhosphoSitePlus
T3742 Phosphorylation PhosphoSitePlus
K3862 Acetylation PhosphoSitePlus
K3864 Acetylation PhosphoSitePlus
K3868 Acetylation PhosphoSitePlus
K3873 Acetylation PhosphoSitePlus
S3887 Phosphorylation PhosphoSitePlus
K3888 Acetylation PhosphoSitePlus
T3957 Phosphorylation PhosphoSitePlus
T3969 Phosphorylation PhosphoSitePlus
T3970 Phosphorylation PhosphoSitePlus
T3973 Phosphorylation PhosphoSitePlus
T3974 Phosphorylation PhosphoSitePlus
T3981 Phosphorylation PhosphoSitePlus
S4004 Phosphorylation PhosphoSitePlus
T4007 Phosphorylation PhosphoSitePlus
T4051 Phosphorylation PhosphoSitePlus
S4078 Phosphorylation PhosphoSitePlus
T4081 Phosphorylation PhosphoSitePlus
S4115 Phosphorylation PhosphoSitePlus
S4134 Phosphorylation PhosphoSitePlus
T4143 Phosphorylation PhosphoSitePlus
Y4177 Phosphorylation PhosphoSitePlus
S4181 Phosphorylation PhosphoSitePlus
T4219 Phosphorylation PhosphoSitePlus
S4229 Phosphorylation PhosphoSitePlus   UniProt 24275569
S4253 Phosphorylation PhosphoSitePlus
T4258 Phosphorylation PhosphoSitePlus
Y4266 Phosphorylation PhosphoSitePlus
S4278 Phosphorylation PhosphoSitePlus
S4290 Phosphorylation PhosphoSitePlus   UniProt 24275569
S4298 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 21406692, 17287340, ...24275569
Y4303 Phosphorylation PhosphoSitePlus
S4306 Phosphorylation PhosphoSitePlus
S4325 Phosphorylation PhosphoSitePlus
K4327 Acetylation PhosphoSitePlus
K4328 Acetylation PhosphoSitePlus
S4330 Phosphorylation PhosphoSitePlus
S4333 Phosphorylation PhosphoSitePlus
K4338 Ubiquitination PhosphoSitePlus
S4342 Phosphorylation PhosphoSitePlus
S4349 Phosphorylation PhosphoSitePlus
S4350 Phosphorylation PhosphoSitePlus   UniProt 23186163
Site PTM Type PTM Enzyme Score Source PMID
S847 Phosphorylation HPRD 18452278
S861 Phosphorylation HPRD 18452278
S867 Phosphorylation HPRD 18452278
Y902 Phosphorylation HPRD 17322306, 18767875
S906 Phosphorylation HPRD 17322306, 18767875
S913 Phosphorylation HPRD 19651622
S916 Phosphorylation HPRD 19651622
S918 Phosphorylation HPRD 19651622
S922 Phosphorylation HPRD 19651622
S1445 Phosphorylation HPRD 20068231
T1454 Phosphorylation HPRD 20068231
S1666 Phosphorylation HPRD 19413330
T2909 Phosphorylation HPRD 20068231
S2912 Phosphorylation HPRD 20068231
S4048 Phosphorylation HPRD 20068231
T4050 Phosphorylation HPRD 20068231
T4051 Phosphorylation HPRD 20068231
S4298 Phosphorylation HPRD 20166139, 17287340
Y4303 Phosphorylation HPRD 19901323
Site PTM Type PTM Enzyme Score Source PMID
S22 Phosphorylation PhosphoSitePlus
S27 Phosphorylation PhosphoSitePlus
Y28 Phosphorylation PhosphoSitePlus
S844 Phosphorylation PhosphoSitePlus
Y848 Phosphorylation PhosphoSitePlus
S850 Phosphorylation PhosphoSitePlus
Y861 Phosphorylation PhosphoSitePlus
T881 Phosphorylation PhosphoSitePlus
Y884 Phosphorylation PhosphoSitePlus
Y1461 Phosphorylation PhosphoSitePlus
S1462 Phosphorylation PhosphoSitePlus
Y1463 Phosphorylation PhosphoSitePlus
T1465 Phosphorylation PhosphoSitePlus
S1470 Phosphorylation PhosphoSitePlus
S1473 Phosphorylation PhosphoSitePlus
Y1614 Phosphorylation PhosphoSitePlus
S1632 Phosphorylation PhosphoSitePlus
S1638 Phosphorylation PhosphoSitePlus
S1645 Phosphorylation PhosphoSitePlus
S1658 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S1444 Phosphorylation PhosphoSitePlus
Y1454 Phosphorylation PhosphoSitePlus
S1455 Phosphorylation PhosphoSitePlus
Y1456 Phosphorylation PhosphoSitePlus
T1458 Phosphorylation PhosphoSitePlus
S1463 Phosphorylation PhosphoSitePlus
S1466 Phosphorylation PhosphoSitePlus
Y1607 Phosphorylation PhosphoSitePlus
S1625 Phosphorylation PhosphoSitePlus
S1631 Phosphorylation PhosphoSitePlus
S1638 Phosphorylation PhosphoSitePlus
S1651 Phosphorylation PhosphoSitePlus
Y1750 Phosphorylation PhosphoSitePlus
S1762 Phosphorylation PhosphoSitePlus
Y1787 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y36 Phosphorylation HPRD 17322306, 18767875
S40 Phosphorylation HPRD 17322306, 18767875
S47 Phosphorylation HPRD 19651622
S50 Phosphorylation HPRD 19651622
S52 Phosphorylation HPRD 19651622
S56 Phosphorylation HPRD 19651622
S606 Phosphorylation HPRD 19664995
S922 Phosphorylation HPRD 20166139, 17287340
Y927 Phosphorylation HPRD 19901323
Site PTM Type PTM Enzyme Score Source PMID
S468 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S39 F39 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S44 C44 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S531 F531 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y740 H740 Biomuta DOID:363 / uterine cancer [ tcga ]
Y808 C808 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S810 L810 Biomuta DOID:1115 / sarcoma [ icgc, tcga ]
T814 I814 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
S896 Y896 Biomuta DOID:3571 / liver cancer [ icgc ]
S916 F916 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S919 L919 Biomuta DOID:363 / uterine cancer [ cosmic, tcga ] DOID:1612 / breast cancer [ icgc, tcga ]
S922 P922 Biomuta DOID:10534 / stomach cancer [ tcga ]
S959 Y959 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ]
S964 N964 Biomuta DOID:11934 / head and neck cancer [ tcga ]
S1462 F1462 Biomuta DOID:1909 / melanoma [ tcga ]
S1551 F1551 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
T1624 N1624 Biomuta DOID:3571 / liver cancer [ icgc ]
S1690 L1690 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S1691 T1691 Biomuta DOID:2531 / hematologic cancer [ icgc ]
T1695 I1695 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
K1838 R1838 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
S1976 L1976 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
K2058 T2058 Biomuta DOID:9256 / colorectal cancer [ tcga ]
S2085 F2085 Biomuta DOID:363 / uterine cancer [ tcga ]
S2146 R2146 Biomuta DOID:3571 / liver cancer [ icgc ]
T2147 A2147 Biomuta DOID:363 / uterine cancer [ tcga ]
S2858 L2858 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S3513 L3513 Biomuta DOID:1324 / lung cancer [ tcga ]
S3712 F3712 Biomuta DOID:263 / kidney cancer [ cosmic, tcga ]
S4048 L4048 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
T4051 M4051 Biomuta DOID:5041 / esophageal cancer [ icgc ]
S4115 * Biomuta DOID:1793 / pancreatic cancer [ tcga ]
S4229 I4229 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S4306 F4306 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
S4306 A4306 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ]
S4306 Y4306 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
S4333 Y4333 Biomuta DOID:9256 / colorectal cancer [ tcga ] DOID:1909 / melanoma [ cosmic ]
S4342 N4342 Biomuta DOID:1793 / pancreatic cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]