iPTMnet Report for Q12913 (PTPRJ)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q12913 / PTPRJ_HUMAN
Protein Name Receptor-type tyrosine-protein phosphatase eta precursor
Gene Name Name: PTPRJ
Synonyms:DEP1;
Organism Homo sapiens (Human)

PRO ID PR:Q12913
DAG View
PRO Name receptor-type tyrosine-protein phosphatase eta (human)
Definition A receptor-type tyrosine-protein phosphatase eta that is encoded in the genome of human.
Short Label hPTPRJ
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q12913 (PTPRJ) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T59 O-Glycosylation GlyGen 25813380
S62 O-Glycosylation GlyGen 25813380
S63 O-Glycosylation GlyGen 25813380
T64 O-Glycosylation GlyGen 30459171, 25813380
T98 O-Glycosylation GlyGen 25813380
N104 N-Glycosylation GlyGen 24190977
N142 N-Glycosylation GlyGen 24190977
S226 Phosphorylation PhosphoSitePlus
N229 N-Glycosylation GlyGen 24190977
N231 N-Glycosylation GlyGen 29391424, 24190977
T233 Phosphorylation PhosphoSitePlus
N258 N-Glycosylation GlyGen 24190977
N278 N-Glycosylation GlyGen 24190977
T305 O-Glycosylation GlyGen 30459171, 25813380
N342 N-Glycosylation GlyGen   UniProt 16335952, 29391424, 24190977
N351 N-Glycosylation GlyGen   UniProt 16335952, 24190977
N391 N-Glycosylation GlyGen   UniProt 16335952, 24190977
N396 N-Glycosylation GlyGen   UniProt 16335952, 24190977
N411 N-Glycosylation GlyGen 24190977
N413 N-Glycosylation GlyGen   UniProt 29391424, 19159218, 24190977
N431 N-Glycosylation GlyGen 24190977
N501 N-Glycosylation GlyGen 29741879
N525 N-Glycosylation GlyGen 24190977
N582 N-Glycosylation GlyGen 24190977
N824 N-Glycosylation GlyGen 24190977
N831 N-Glycosylation GlyGen 24190977
N937 N-Glycosylation GlyGen   UniProt 19159218, 24190977
S1009 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1011 Phosphorylation PhosphoSitePlus
K1014 Ubiquitination PhosphoSitePlus
K1031 Acetylation PhosphoSitePlus
K1031 Ubiquitination PhosphoSitePlus
K1032 Ubiquitination PhosphoSitePlus
K1049 Ubiquitination PhosphoSitePlus
K1057 Ubiquitination PhosphoSitePlus
Y1071 Phosphorylation PhosphoSitePlus
Y1077 Phosphorylation PhosphoSitePlus
T1091 Phosphorylation PhosphoSitePlus
Y1094 Phosphorylation PhosphoSitePlus
Y1099 Phosphorylation PhosphoSitePlus
Y1103 Phosphorylation PhosphoSitePlus
S1105 Phosphorylation PhosphoSitePlus
Y1133 Phosphorylation PhosphoSitePlus
T1139 Phosphorylation PhosphoSitePlus
Y1225 Phosphorylation PhosphoSitePlus
K1306 Ubiquitination PhosphoSitePlus
Y1311 Phosphorylation PhosphoSitePlus   RLIMS-P 22898603
Y1311 Phosphorylation P06241 (FYN) PhosphoSitePlus 22898603
Y1311 Phosphorylation P12931 (SRC) PhosphoSitePlus 22898603
T1314 Phosphorylation PhosphoSitePlus
T1318 Phosphorylation PhosphoSitePlus   RLIMS-P 24583284
Y1320 Phosphorylation PhosphoSitePlus   RLIMS-P 22898603, 24583284
Y1320 Phosphorylation P06241 (FYN) PhosphoSitePlus 22898603
Y1320 Phosphorylation P12931 (SRC) PhosphoSitePlus 22898603
Site PTM Type PTM Enzyme Score Source PMID
S1009 Phosphorylation HPRD 20068231
S1011 Phosphorylation HPRD 19651622
T1201 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N258 S258 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
N431 S431 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S1011 A1011 Biomuta DOID:4159 / skin cancer [ cosmic ]
K1032 T1032 Biomuta DOID:363 / uterine cancer [ icgc ]
Y1094 C1094 Biomuta DOID:1612 / breast cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ]
S1105 F1105 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y1133 C1133 Biomuta DOID:1324 / lung cancer [ cosmic ]
T1318 S1318 Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y1320 S1320 Biomuta DOID:263 / kidney cancer [ cosmic ]
Y1320 F1320 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]