iPTMnet Report for Q12908 (SLC10A2)
Protein Information
UniProt AC / UniProt ID | Q12908 / NTCP2_HUMAN |
Protein Name | Ileal sodium/bile acid cotransporter |
Gene Name | Name: SLC10A2 Synonyms:ASBT,ISBT,NTCP2; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q12908 |
PRO Name | ileal sodium/bile acid cotransporter (human) |
Definition | An ileal sodium/bile acid cotransporter that is encoded in the genome of human. |
Short Label | hSLC10A2 |
Category | organism-gene |
Q12908 (SLC10A2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
N10 | N-Glycosylation | score3 | GlyGen UniProt | 15350125 | ||
K312 | Methylation | score1 | PhosphoSitePlus | |||
K313 | Methylation | score1 | PhosphoSitePlus | |||
S335 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S335 | L335 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] |