iPTMnet Report for Q12907 (LMAN2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q12907 / LMAN2_HUMAN
Protein Name Vesicular integral-membrane protein VIP36 precursor
Gene Name Name: LMAN2
Synonyms:C5orf8;
Organism Homo sapiens (Human)

PRO ID PR:Q12907
DAG View
PRO Name vesicular integral-membrane protein VIP36 (human)
Definition A vesicular integral-membrane protein VIP36 that is encoded in the genome of human.
Short Label hLMAN2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q12907 (LMAN2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T91 O-Glycosylation GlyGen 25813380
K126 Ubiquitination PhosphoSitePlus
S178 Phosphorylation PhosphoSitePlus
N182 N-Glycosylation GlyGen 24190977
N183 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 12754519, ...24190977
T213 Phosphorylation HPRD   PhosphoSitePlus 20068231
T225 Phosphorylation PhosphoSitePlus
T228 Phosphorylation PhosphoSitePlus
T249 Phosphorylation PhosphoSitePlus
Y251 Phosphorylation PhosphoSitePlus
Y252 Phosphorylation PhosphoSitePlus
S263 Phosphorylation PhosphoSitePlus
K291 Ubiquitination PhosphoSitePlus
S295 Phosphorylation PhosphoSitePlus
K300 Ubiquitination PhosphoSitePlus
K303 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T91 I91 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K126 N126 Biomuta DOID:363 / uterine cancer [ icgc ]
S178 L178 Biomuta DOID:4159 / skin cancer [ cosmic ]
N182 T182 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T225 M225 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S263 F263 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic, icgc ]
K291 N291 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]