Protein Information

Cytoscape View


UniProt AC / UniProt ID Q12904 / AIMP1_HUMAN
Protein Name Aminoacyl tRNA synthase complex-interacting multifunctional protein 1
Gene Name Name: AIMP1
Synonyms:EMAP2,SCYE1;
Organism Homo sapiens (Human)

PRO ID PR:Q12904
DAG View
PRO Name aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (human)
Definition An aminoacyl tRNA synthase complex-interacting multifunctional protein 1 that is encoded in the genome of human.
Short Label hAIMP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q12904 (AIMP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 24312579, 22814378, 22223895
K9 Ubiquitination PhosphoSitePlus
Y24 Phosphorylation PhosphoSitePlus
K26 Ubiquitination PhosphoSitePlus
K33 Acetylation PhosphoSitePlus
K33 Ubiquitination PhosphoSitePlus
K35 Ubiquitination PhosphoSitePlus
T41 Phosphorylation PhosphoSitePlus
K63 Acetylation PhosphoSitePlus
K63 Ubiquitination PhosphoSitePlus
S90 Phosphorylation PhosphoSitePlus
K137 Sumoylation PhosphoSitePlus
S140 Phosphorylation P45983 (MAPK8) PhosphoSitePlus   RLIMS-P   Signor   UniProt 20510162, 23186163
S144 Phosphorylation PhosphoSitePlus
C161 S-Nitrosylation dbSNO 19483679
T164 Phosphorylation P45983 (MAPK8) neXtProt 20510162
S173 Phosphorylation PhosphoSitePlus
Y175 Phosphorylation PhosphoSitePlus
R187 Methylation PhosphoSitePlus
R205 Methylation PhosphoSitePlus
S223 Phosphorylation PhosphoSitePlus
R250 Methylation PhosphoSitePlus
K262 Acetylation PhosphoSitePlus
K267 Acetylation PhosphoSitePlus
K269 Ubiquitination PhosphoSitePlus
K312 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T84 Phosphorylation HPRD 20068231
S99 Phosphorylation HPRD 20068231
S107 Phosphorylation HPRD 20068231
T109 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
K24 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 T2 Biomuta DOID:1324 / lung cancer [ cosmic ]
T41 N41 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
T41 P41 Biomuta DOID:363 / uterine cancer [ tcga ]
S90 Y90 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S173 Y173 Biomuta DOID:363 / uterine cancer [ tcga ]
R205 W205 Biomuta DOID:363 / uterine cancer [ tcga ]
R250 I250 Biomuta DOID:363 / uterine cancer [ tcga ]
R250 T250 Biomuta DOID:2531 / hematologic cancer [ tcga ]
K267 N267 Biomuta DOID:363 / uterine cancer [ tcga ]