Protein Information

Cytoscape View


UniProt AC / UniProt ID Q12891 / HYAL2_HUMAN
Protein Name Hyaluronidase-2 precursor
Gene Name Name: HYAL2
Synonyms:LUCA2;
Organism Homo sapiens (Human)

PRO ID PR:Q12891
DAG View
PRO Name hyaluronidase-2 (human)
Definition A hyaluronidase-2 that is encoded in the genome of human.
Short Label hHYAL2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q12891 (HYAL2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K148 Ubiquitination PhosphoSitePlus
T190 Phosphorylation PhosphoSitePlus
Y216 Phosphorylation PhosphoSitePlus   RLIMS-P 31123603
Y291 Phosphorylation PhosphoSitePlus
T297 Phosphorylation PhosphoSitePlus
Y298 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K148 E148 Biomuta DOID:11934 / head and neck cancer [ icgc, tcga ]
Y291 C291 Biomuta DOID:1909 / melanoma [ cosmic ]