iPTMnet Report Q12891 HYAL2

Protein Information

Cytoscape View

UniProt AC / UniProt ID	Q12891 / HYAL2_HUMAN
Protein Name	Hyaluronidase-2 precursor
Gene Name	Name: HYAL2 Synonyms:LUCA2;
Organism	Homo sapiens (Human)

PRO ID	PR:Q12891 DAG View
PRO Name	hyaluronidase-2 (human)
Definition	A hyaluronidase-2 that is encoded in the genome of human.
Short Label	hHYAL2
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q12891 (HYAL2) as Substrate

Q12891

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	T26	O-Glycosylation		score1	GlyGen	25813380
	T32	O-Glycosylation		score1	GlyGen	25813380
	N103	N-Glycosylation		score1	GlyGen	24190977
	K148	Ubiquitination		score1	PhosphoSitePlus
	T190	Phosphorylation		score1	PhosphoSitePlus
	Y216	Phosphorylation		score3	PhosphoSitePlus RLIMS-P	31123603
	Y291	Phosphorylation		score1	PhosphoSitePlus
	T297	Phosphorylation		score1	PhosphoSitePlus
	Y298	Phosphorylation		score1	PhosphoSitePlus

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
K148	E148	Biomuta		DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
Y291	C291	Biomuta		DOID:9256 / colorectal cancer [ cosmic ]