iPTMnet Report for Q12836 (ZP4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q12836 / ZP4_HUMAN
Protein Name Zona pellucida sperm-binding protein 4 precursor
Gene Name Name: ZP4
Synonyms:ZPB;
Organism Homo sapiens (Human)

PRO ID PR:Q12836
DAG View
PRO Name zona pellucida sperm-binding protein 4 (human)
Definition A zona pellucida sperm-binding protein 4 that is encoded in the genome of human.
Short Label hZP4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q12836 (ZP4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y327 Phosphorylation PhosphoSitePlus
Y330 Phosphorylation PhosphoSitePlus
Y331 Phosphorylation PhosphoSitePlus
Y347 Phosphorylation PhosphoSitePlus
Y390 Phosphorylation PhosphoSitePlus
Y395 Phosphorylation PhosphoSitePlus
T428 Phosphorylation PhosphoSitePlus
S471 Phosphorylation PhosphoSitePlus
T475 Phosphorylation PhosphoSitePlus
S504 Phosphorylation PhosphoSitePlus
S513 Phosphorylation PhosphoSitePlus
Y525 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y331 C331 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
Y347 * Biomuta DOID:1324 / lung cancer [ cosmic ]
Y395 C395 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T475 S475 Biomuta DOID:1324 / lung cancer [ cosmic ]
S513 C513 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]