Protein Information

Cytoscape View


UniProt AC / UniProt ID Q12830 / BPTF_HUMAN
Protein Name Nucleosome-remodeling factor subunit BPTF
Gene Name Name: BPTF
Synonyms:FAC1,FALZ;
Organism Homo sapiens (Human)

PRO ID PR:Q12830
DAG View
PRO Name nucleosome-remodeling factor subunit BPTF (human)
Definition A nucleosome-remodeling factor subunit BPTF that is encoded in the genome of human.
Short Label hBPTF
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q12830 (BPTF) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R5 Methylation PhosphoSitePlus
R7 Methylation PhosphoSitePlus
K10 Methylation PhosphoSitePlus
R40 Methylation PhosphoSitePlus
R63 Methylation PhosphoSitePlus
R68 Methylation PhosphoSitePlus
R74 Methylation PhosphoSitePlus
T87 Phosphorylation PhosphoSitePlus
S88 Phosphorylation PhosphoSitePlus
R92 Methylation PhosphoSitePlus
S198 Phosphorylation PhosphoSitePlus
T199 Phosphorylation PhosphoSitePlus
S201 Phosphorylation PhosphoSitePlus
S202 Phosphorylation PhosphoSitePlus
T203 Phosphorylation PhosphoSitePlus
S216 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163, 19690332, ...20068231
K338 Ubiquitination PhosphoSitePlus
K360 Ubiquitination PhosphoSitePlus
K362 Ubiquitination PhosphoSitePlus
T374 Phosphorylation PhosphoSitePlus
Y463 Phosphorylation PhosphoSitePlus
T483 Phosphorylation PhosphoSitePlus
K509 Ubiquitination PhosphoSitePlus
K540 Ubiquitination PhosphoSitePlus
K546 Ubiquitination PhosphoSitePlus
K564 Methylation PhosphoSitePlus
K571 Methylation PhosphoSitePlus
S572 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163
S601 Phosphorylation PhosphoSitePlus
T610 Phosphorylation PhosphoSitePlus
T645 Phosphorylation PhosphoSitePlus
S650 Phosphorylation PhosphoSitePlus
S656 Phosphorylation PhosphoSitePlus
S737 Phosphorylation PhosphoSitePlus
T739 Phosphorylation PhosphoSitePlus
S742 Phosphorylation PhosphoSitePlus
K755 Acetylation PhosphoSitePlus
S756 Phosphorylation PhosphoSitePlus
S761 Phosphorylation PhosphoSitePlus
S763 Phosphorylation PhosphoSitePlus   UniProt 18669648, 21406692, 20068231
K791 Ubiquitination PhosphoSitePlus
K804 Ubiquitination PhosphoSitePlus
S817 Phosphorylation PhosphoSitePlus   UniProt 17525332
S822 Phosphorylation PhosphoSitePlus
K833 Methylation PhosphoSitePlus
K833 Ubiquitination PhosphoSitePlus
K841 Ubiquitination PhosphoSitePlus
K847 Ubiquitination PhosphoSitePlus
Y848 Phosphorylation PhosphoSitePlus
Y851 Phosphorylation PhosphoSitePlus
K864 Ubiquitination PhosphoSitePlus
K880 Acetylation PhosphoSitePlus   UniProt 19608861
K880 Ubiquitination PhosphoSitePlus
T909 Phosphorylation PhosphoSitePlus
T911 Phosphorylation PhosphoSitePlus
K942 Ubiquitination PhosphoSitePlus
S980 Phosphorylation PhosphoSitePlus
K1009 Ubiquitination PhosphoSitePlus
K1015 Ubiquitination PhosphoSitePlus
K1020 Ubiquitination PhosphoSitePlus
K1048 Ubiquitination PhosphoSitePlus
S1060 Phosphorylation PhosphoSitePlus
T1064 Phosphorylation PhosphoSitePlus   UniProt 21406692, 17081983
S1075 Phosphorylation PhosphoSitePlus
K1088 Sumoylation PhosphoSitePlus
S1131 Phosphorylation PhosphoSitePlus
S1133 Phosphorylation PhosphoSitePlus
K1185 Ubiquitination PhosphoSitePlus
K1202 Ubiquitination PhosphoSitePlus
K1215 Ubiquitination PhosphoSitePlus
K1226 Ubiquitination PhosphoSitePlus
S1231 Phosphorylation PhosphoSitePlus   UniProt 21406692
T1235 Phosphorylation PhosphoSitePlus
S1243 Phosphorylation PhosphoSitePlus
S1245 Phosphorylation PhosphoSitePlus
S1251 Phosphorylation PhosphoSitePlus
S1277 Phosphorylation PhosphoSitePlus
Y1287 Phosphorylation PhosphoSitePlus
S1297 Phosphorylation PhosphoSitePlus
S1300 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163, 21406692
T1303 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1310 Phosphorylation PhosphoSitePlus   UniProt 21406692, 20068231
K1335 Ubiquitination PhosphoSitePlus
K1345 Ubiquitination PhosphoSitePlus
K1358 Ubiquitination PhosphoSitePlus
S1381 Phosphorylation PhosphoSitePlus
S1382 Phosphorylation PhosphoSitePlus
K1385 Ubiquitination PhosphoSitePlus
S1386 Phosphorylation PhosphoSitePlus
T1393 Phosphorylation PhosphoSitePlus
S1396 Phosphorylation PhosphoSitePlus
S1467 Phosphorylation PhosphoSitePlus
R1474 Methylation PhosphoSitePlus
K1539 Acetylation PhosphoSitePlus
K1545 Ubiquitination PhosphoSitePlus
K1550 Ubiquitination PhosphoSitePlus
K1565 Ubiquitination PhosphoSitePlus
K1571 Ubiquitination PhosphoSitePlus
K1579 Ubiquitination PhosphoSitePlus
K1610 Ubiquitination PhosphoSitePlus
S1616 Phosphorylation PhosphoSitePlus
S1617 Phosphorylation PhosphoSitePlus
Y1623 Phosphorylation PhosphoSitePlus
S1626 Phosphorylation PhosphoSitePlus
T1629 Phosphorylation PhosphoSitePlus
T1639 Phosphorylation PhosphoSitePlus
T1676 Phosphorylation PhosphoSitePlus
S1677 Phosphorylation PhosphoSitePlus
S1681 Phosphorylation PhosphoSitePlus
S1684 Phosphorylation PhosphoSitePlus
T1709 Phosphorylation PhosphoSitePlus
T1712 Phosphorylation PhosphoSitePlus
T1715 Phosphorylation PhosphoSitePlus
T1716 Phosphorylation PhosphoSitePlus
S1725 Phosphorylation PhosphoSitePlus
K1730 Sumoylation PhosphoSitePlus
K1736 Ubiquitination PhosphoSitePlus
S1749 O-Glycosylation PhosphoSitePlus
T1753 O-Glycosylation PhosphoSitePlus
S1762 Phosphorylation PhosphoSitePlus
T1763 Phosphorylation PhosphoSitePlus
S1769 Phosphorylation PhosphoSitePlus
K1776 Ubiquitination PhosphoSitePlus
T1793 Phosphorylation PhosphoSitePlus
S1805 Phosphorylation PhosphoSitePlus
S1809 Phosphorylation PhosphoSitePlus
S1827 Phosphorylation PhosphoSitePlus
T1829 Phosphorylation PhosphoSitePlus
S1833 Phosphorylation PhosphoSitePlus
K1844 Ubiquitination PhosphoSitePlus
K1855 Ubiquitination PhosphoSitePlus
K1874 Ubiquitination PhosphoSitePlus
T1899 Phosphorylation PhosphoSitePlus
S1902 Phosphorylation PhosphoSitePlus
S1907 Phosphorylation PhosphoSitePlus
K1949 Ubiquitination PhosphoSitePlus
K1966 Ubiquitination PhosphoSitePlus
T1976 Phosphorylation PhosphoSitePlus
K1978 Ubiquitination PhosphoSitePlus
T1980 Phosphorylation PhosphoSitePlus
T1982 Phosphorylation PhosphoSitePlus
K1996 Ubiquitination PhosphoSitePlus
K2034 Ubiquitination PhosphoSitePlus
T2056 Phosphorylation PhosphoSitePlus
T2058 Phosphorylation PhosphoSitePlus
T2059 Phosphorylation PhosphoSitePlus
T2065 Phosphorylation PhosphoSitePlus
S2070 Phosphorylation PhosphoSitePlus
S2081 O-Glycosylation PhosphoSitePlus
T2094 O-Glycosylation PhosphoSitePlus
K2095 Ubiquitination PhosphoSitePlus
S2098 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
T2103 O-Glycosylation PhosphoSitePlus
K2119 Ubiquitination PhosphoSitePlus
R2155 Methylation PhosphoSitePlus   UniProt 24129315
R2162 Methylation PhosphoSitePlus   UniProt 24129315
R2184 Methylation PhosphoSitePlus   UniProt 24129315
R2191 Methylation PhosphoSitePlus   UniProt 24129315
T2192 Phosphorylation PhosphoSitePlus
S2197 Phosphorylation PhosphoSitePlus
K2201 Ubiquitination PhosphoSitePlus
R2205 Methylation PhosphoSitePlus
T2206 Phosphorylation PhosphoSitePlus
S2239 Phosphorylation PhosphoSitePlus
T2241 Phosphorylation PhosphoSitePlus
T2251 Phosphorylation PhosphoSitePlus
S2252 Phosphorylation PhosphoSitePlus
S2259 Phosphorylation PhosphoSitePlus
R2265 Methylation PhosphoSitePlus
T2342 Phosphorylation PhosphoSitePlus
T2346 Phosphorylation PhosphoSitePlus
T2349 Phosphorylation PhosphoSitePlus
S2355 Phosphorylation PhosphoSitePlus
T2356 Phosphorylation PhosphoSitePlus
T2357 Phosphorylation PhosphoSitePlus
S2370 Phosphorylation PhosphoSitePlus
S2459 Phosphorylation PhosphoSitePlus
S2465 Phosphorylation PhosphoSitePlus   UniProt 21406692
S2471 Phosphorylation PhosphoSitePlus
S2473 Phosphorylation PhosphoSitePlus
T2475 Phosphorylation PhosphoSitePlus
T2481 Phosphorylation PhosphoSitePlus
S2486 Phosphorylation PhosphoSitePlus
T2497 Phosphorylation PhosphoSitePlus
K2648 Ubiquitination PhosphoSitePlus
S2659 Phosphorylation PhosphoSitePlus
K2678 Ubiquitination PhosphoSitePlus
K2681 Acetylation PhosphoSitePlus
S2682 Phosphorylation PhosphoSitePlus
T2684 Phosphorylation PhosphoSitePlus
Y2703 Phosphorylation PhosphoSitePlus
K2707 Ubiquitination PhosphoSitePlus
K2772 Ubiquitination PhosphoSitePlus
S2812 Phosphorylation PhosphoSitePlus
T2827 Phosphorylation PhosphoSitePlus
S2859 Phosphorylation PhosphoSitePlus
Y2964 Phosphorylation PhosphoSitePlus
Y2985 Phosphorylation PhosphoSitePlus
Y2986 Phosphorylation PhosphoSitePlus
T2990 Phosphorylation PhosphoSitePlus
T2997 Phosphorylation PhosphoSitePlus
K3040 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S33 Phosphorylation PhosphoSitePlus
S41 Phosphorylation PhosphoSitePlus
R68 Methylation PhosphoSitePlus
S216 Phosphorylation HPRD 18669648, 15302935, 19007248, ...20068231, 18452278
S572 Phosphorylation HPRD 19651622, 17081983, 18452278
S601 Phosphorylation HPRD 18452278
S637 Phosphorylation HPRD 19413330, 18669648, 15302935, ...20068231, 20068230
S691 Phosphorylation HPRD 17525332
T938 Phosphorylation HPRD 17081983
S1105 Phosphorylation HPRD 19413330, 20068231
S1145 Phosphorylation HPRD 20068231
S1171 Phosphorylation HPRD 17081983
S1174 Phosphorylation HPRD 18669648, 20068231, 18452278
T1177 Phosphorylation HPRD 17081983, 20068231
S1184 Phosphorylation HPRD 20068231
T1545 Phosphorylation HPRD 20068231
T1586 Phosphorylation HPRD 19413330
T1589 Phosphorylation HPRD 19413330
T1590 Phosphorylation HPRD 19413330
T1637 Phosphorylation HPRD 20068231
S1701 Phosphorylation HPRD 17081983
S1707 Phosphorylation HPRD 17081983
S1972 Phosphorylation HPRD 18669648, 20068231
T2115 Phosphorylation PhosphoSitePlus
S2241 Phosphorylation HPRD 20068231
S2244 Phosphorylation HPRD 19651622, 17081983, 20068231, ...18452278
Site PTM Type PTM Enzyme Score Source PMID
S216 Phosphorylation HPRD 18669648, 15302935, 19007248, ...20068231, 18452278
S572 Phosphorylation HPRD 19651622, 17081983, 18452278
S601 Phosphorylation HPRD 18452278
S763 Phosphorylation HPRD 19413330, 18669648, 15302935, ...20068231, 20068230
S817 Phosphorylation HPRD 17525332
T1064 Phosphorylation HPRD 17081983
S1231 Phosphorylation HPRD 19413330, 20068231
S1271 Phosphorylation HPRD 20068231
S1297 Phosphorylation HPRD 17081983
S1300 Phosphorylation HPRD 18669648, 20068231, 18452278
T1303 Phosphorylation HPRD 17081983, 20068231
S1310 Phosphorylation HPRD 20068231
T1671 Phosphorylation HPRD 20068231
T1712 Phosphorylation HPRD 19413330
T1715 Phosphorylation HPRD 19413330
T1716 Phosphorylation HPRD 19413330
T1763 Phosphorylation HPRD 20068231
S1827 Phosphorylation HPRD 17081983
S1833 Phosphorylation HPRD 17081983
S2098 Phosphorylation HPRD 18669648, 20068231
T2241 Phosphorylation PhosphoSitePlus
S2367 Phosphorylation HPRD 20068231
S2370 Phosphorylation HPRD 19651622, 17081983, 20068231, ...18452278
S2480 Phosphorylation PhosphoSitePlus
T2481 Phosphorylation PhosphoSitePlus
S2483 Phosphorylation HPRD   PhosphoSitePlus 18669648
S2486 Phosphorylation PhosphoSitePlus
S2491 Phosphorylation HPRD 18669648
T2496 Phosphorylation PhosphoSitePlus
S2498 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S202 G202 Biomuta DOID:5041 / esophageal cancer [ tcga ]
S202 I202 Biomuta DOID:363 / uterine cancer [ tcga ]
K338 * Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
T483 A483 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
K509 T509 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
S650 G650 Biomuta DOID:1324 / lung cancer [ tcga ]
S656 N656 Biomuta DOID:9256 / colorectal cancer [ tcga ]
K804 T804 Biomuta DOID:363 / uterine cancer [ cosmic, tcga ] DOID:9256 / colorectal cancer [ icgc, tcga ]
K804 E804 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
T909 I909 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
K1009 T1009 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
K1048 R1048 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
K1358 N1358 Biomuta DOID:4362 / cervical cancer [ tcga ] DOID:1324 / lung cancer [ tcga ]
S1381 L1381 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S1626 N1626 Biomuta DOID:363 / uterine cancer [ tcga ]
S1749 P1749 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S1749 C1749 Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]
S1907 N1907 Biomuta DOID:1324 / lung cancer [ cosmic ]
T1980 M1980 Biomuta DOID:363 / uterine cancer [ tcga ]
T2059 S2059 Biomuta DOID:1324 / lung cancer [ tcga ]
S2070 T2070 Biomuta DOID:3963 / thyroid carcinoma [ cosmic ]
S2070 C2070 Biomuta DOID:3963 / thyroid carcinoma [ cosmic ]
T2103 I2103 Biomuta DOID:263 / kidney cancer [ cosmic ]
R2155 S2155 Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]
R2184 H2184 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
R2184 C2184 Biomuta DOID:1909 / melanoma [ cosmic ]
R2191 T2191 Biomuta DOID:1612 / breast cancer [ cosmic, tcga ] DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
S2465 F2465 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
K2648 R2648 Biomuta DOID:1909 / melanoma [ tcga ]
S2682 N2682 Biomuta DOID:9256 / colorectal cancer [ tcga ]