iPTMnet Report for Q12816 (TRO)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q12816 / TROP_HUMAN
Protein Name Trophinin
Gene Name Name: TRO
Synonyms:KIAA1114,MAGED3;
Organism Homo sapiens (Human)

PRO ID PR:Q12816
DAG View
PRO Name trophinin (human)
Definition A trophinin that is encoded in the genome of human.
Short Label hTRO
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q12816 (TRO) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T78 Phosphorylation PhosphoSitePlus
K81 Ubiquitination PhosphoSitePlus
K99 Acetylation PhosphoSitePlus
T146 Phosphorylation PhosphoSitePlus
S153 Phosphorylation PhosphoSitePlus
S155 Phosphorylation PhosphoSitePlus
T157 Phosphorylation PhosphoSitePlus
S168 Phosphorylation PhosphoSitePlus
K266 Ubiquitination PhosphoSitePlus
K298 Acetylation PhosphoSitePlus
K299 Acetylation PhosphoSitePlus
K301 Acetylation PhosphoSitePlus
T334 Phosphorylation PhosphoSitePlus
S413 Phosphorylation PhosphoSitePlus
S422 Phosphorylation PhosphoSitePlus
S424 Phosphorylation PhosphoSitePlus
Y426 Phosphorylation PhosphoSitePlus
K453 Ubiquitination PhosphoSitePlus
K458 Ubiquitination PhosphoSitePlus
K462 Ubiquitination PhosphoSitePlus
K466 Ubiquitination PhosphoSitePlus
K495 Ubiquitination PhosphoSitePlus
K502 Ubiquitination PhosphoSitePlus
K578 Ubiquitination PhosphoSitePlus
K586 Ubiquitination PhosphoSitePlus
K588 Ubiquitination PhosphoSitePlus
K593 Ubiquitination PhosphoSitePlus
K617 Ubiquitination PhosphoSitePlus
K622 Ubiquitination PhosphoSitePlus
K633 Ubiquitination PhosphoSitePlus
T1333 Phosphorylation PhosphoSitePlus
S1339 Phosphorylation PhosphoSitePlus
T1345 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K266 N266 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K301 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S413 Y413 Biomuta DOID:1612 / breast cancer [ cosmic ]
K458 N458 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K462 N462 Biomuta DOID:1319 / brain cancer [ cosmic ]
K588 T588 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K622 T622 Biomuta DOID:1793 / pancreatic cancer [ icgc ] DOID:5041 / esophageal cancer [ cosmic ]
K633 N633 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T1345 S1345 Biomuta DOID:9256 / colorectal cancer [ cosmic ]