Protein Information

Cytoscape View


UniProt AC / UniProt ID Q12802 / AKP13_HUMAN
Protein Name A-kinase anchor protein 13
Gene Name Name: AKAP13
Synonyms:BRX;
Organism Homo sapiens (Human)

PRO ID PR:Q12802
DAG View
PRO Name A-kinase anchor protein 13 (human)
Definition An A-kinase anchor protein 13 that is encoded in the genome of human.
Short Label hAKAP13
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q12802 (AKAP13) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K134 Ubiquitination PhosphoSitePlus
T180 Phosphorylation PhosphoSitePlus
K186 Ubiquitination PhosphoSitePlus
T273 Phosphorylation PhosphoSitePlus
S345 Phosphorylation PhosphoSitePlus
T393 Phosphorylation phospho.ELM 18669648
S395 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S399 Phosphorylation PhosphoSitePlus
S438 Phosphorylation PhosphoSitePlus
S586 Phosphorylation PhosphoSitePlus
Y604 Phosphorylation PhosphoSitePlus
S649 Phosphorylation PhosphoSitePlus
S650 Phosphorylation PhosphoSitePlus
T656 Phosphorylation PhosphoSitePlus
S688 Phosphorylation PhosphoSitePlus
S692 Phosphorylation PhosphoSitePlus
T693 Phosphorylation PhosphoSitePlus
T694 Phosphorylation PhosphoSitePlus
T784 Phosphorylation phospho.ELM 18669648
S786 Phosphorylation PhosphoSitePlus
S790 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
S793 Phosphorylation phospho.ELM 18669648
S795 Phosphorylation PhosphoSitePlus
T797 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T813 Phosphorylation PhosphoSitePlus
T815 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
T822 Phosphorylation PhosphoSitePlus
T946 Phosphorylation PhosphoSitePlus
T953 Phosphorylation PhosphoSitePlus
S967 Phosphorylation PhosphoSitePlus
S981 Phosphorylation PhosphoSitePlus
S983 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 16964243, ...18669648, 19690332, 20068231
S987 Phosphorylation PhosphoSitePlus
S988 Phosphorylation PhosphoSitePlus
T1112 Phosphorylation PhosphoSitePlus
S1123 Phosphorylation PhosphoSitePlus
T1149 Phosphorylation PhosphoSitePlus
T1170 Phosphorylation phospho.ELM 18669648
S1226 Phosphorylation PhosphoSitePlus
T1227 Phosphorylation PhosphoSitePlus
S1229 Phosphorylation PhosphoSitePlus
T1271 Phosphorylation PhosphoSitePlus
S1281 Phosphorylation PhosphoSitePlus
S1282 Phosphorylation PhosphoSitePlus
K1380 Ubiquitination PhosphoSitePlus
T1385 Phosphorylation PhosphoSitePlus
S1411 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1489 Phosphorylation PhosphoSitePlus   UniProt 24275569
S1492 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1507 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y1512 Phosphorylation PhosphoSitePlus
S1540 Phosphorylation PhosphoSitePlus   UniProt 24275569
S1557 Phosphorylation PhosphoSitePlus
S1559 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 17081983
S1565 Phosphorylation P17612 (PRKACA) neXtProt   phospho.ELM   PhosphoSitePlus   Signor   UniProt 17081983, 15229649, 15324660
S1600 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1602 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T1607 Phosphorylation PhosphoSitePlus
S1618 Phosphorylation PhosphoSitePlus
S1642 Phosphorylation PhosphoSitePlus   UniProt 21406692, 19690332
S1645 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 21406692, 19690332
S1647 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 21406692, 19690332
K1670 Methylation PhosphoSitePlus   UniProt 24129315
Y1676 Phosphorylation PhosphoSitePlus
S1679 Phosphorylation PhosphoSitePlus
S1683 Phosphorylation PhosphoSitePlus
S1690 Phosphorylation PhosphoSitePlus
S1731 Phosphorylation PhosphoSitePlus
S1746 Phosphorylation PhosphoSitePlus
S1750 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1837 Phosphorylation PhosphoSitePlus
S1849 Phosphorylation PhosphoSitePlus
S1857 Phosphorylation PhosphoSitePlus
S1876 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332
T1884 Phosphorylation PhosphoSitePlus
T1887 Phosphorylation PhosphoSitePlus
S1895 Phosphorylation PhosphoSitePlus   UniProt 21406692
S1898 Phosphorylation PhosphoSitePlus
S1900 Phosphorylation PhosphoSitePlus
S1902 Phosphorylation PhosphoSitePlus
S1904 Phosphorylation PhosphoSitePlus
S1906 Phosphorylation PhosphoSitePlus
S1927 Phosphorylation PhosphoSitePlus
S1929 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18669648, 20068231
T1930 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 18669648
S1932 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 21406692, 23186163, ...17081983
K1935 Ubiquitination PhosphoSitePlus
S1937 Phosphorylation PhosphoSitePlus
S1942 Phosphorylation PhosphoSitePlus
T1943 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1945 Phosphorylation PhosphoSitePlus
T1947 Phosphorylation phospho.ELM 18669648
S1977 Phosphorylation PhosphoSitePlus
K1983 Ubiquitination PhosphoSitePlus
K2070 Ubiquitination PhosphoSitePlus
K2099 Acetylation PhosphoSitePlus
K2112 Ubiquitination PhosphoSitePlus
Y2115 Phosphorylation PhosphoSitePlus
K2165 Ubiquitination PhosphoSitePlus
K2182 Ubiquitination PhosphoSitePlus
K2191 Ubiquitination PhosphoSitePlus
Y2205 Phosphorylation PhosphoSitePlus
S2212 Phosphorylation PhosphoSitePlus
S2237 Phosphorylation PhosphoSitePlus
K2241 Ubiquitination PhosphoSitePlus
Y2269 Phosphorylation PhosphoSitePlus
S2273 Phosphorylation PhosphoSitePlus
S2278 Phosphorylation PhosphoSitePlus
T2279 Phosphorylation PhosphoSitePlus
S2345 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
T2356 Phosphorylation PhosphoSitePlus
K2362 Ubiquitination PhosphoSitePlus
K2368 Ubiquitination PhosphoSitePlus
K2371 Ubiquitination PhosphoSitePlus
S2390 Phosphorylation PhosphoSitePlus
T2391 Phosphorylation PhosphoSitePlus
S2398 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
T2400 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S2402 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S2409 Phosphorylation PhosphoSitePlus
T2411 Phosphorylation PhosphoSitePlus
S2460 Phosphorylation PhosphoSitePlus
T2467 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
S2473 Phosphorylation PhosphoSitePlus   UniProt 24275569
S2479 Phosphorylation PhosphoSitePlus
S2498 Phosphorylation PhosphoSitePlus
S2561 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S2563 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 18669648
S2566 Phosphorylation PhosphoSitePlus
S2567 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K2589 Ubiquitination PhosphoSitePlus
S2699 Phosphorylation PhosphoSitePlus
S2703 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S2709 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S2711 Phosphorylation PhosphoSitePlus
S2714 Phosphorylation PhosphoSitePlus
S2718 Phosphorylation PhosphoSitePlus
S2720 Phosphorylation PhosphoSitePlus
S2723 Phosphorylation PhosphoSitePlus
S2726 Phosphorylation PhosphoSitePlus
S2728 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 16964243, ...18669648, 24275569, 19690332
S2733 Phosphorylation P17612 (PRKACA) neXtProt   phospho.ELM   PhosphoSitePlus   Signor 15383279
S2749 Phosphorylation PhosphoSitePlus
S2761 Phosphorylation PhosphoSitePlus
S2766 Phosphorylation PhosphoSitePlus
S2802 Phosphorylation PhosphoSitePlus
S2805 Phosphorylation PhosphoSitePlus
C2813 S-Nitrosylation dbSNO 26338901
Site PTM Type PTM Enzyme Score Source PMID
T393 Phosphorylation HPRD 18669648
S395 Phosphorylation HPRD 18669648
S649 Phosphorylation HPRD 20068231
T784 Phosphorylation HPRD 18669648
S790 Phosphorylation HPRD 18669648, 20068231
S793 Phosphorylation HPRD 18669648
T797 Phosphorylation HPRD 18669648
T815 Phosphorylation HPRD 18669648
S981 Phosphorylation HPRD 18691976
S983 Phosphorylation HPRD 19413330, 16964243, 18767875, ...19664994, 19664995, 19651622, 18669648, 20068231
T1170 Phosphorylation HPRD 18669648
S1411 Phosphorylation HPRD 18669648, 20068231
S1492 Phosphorylation HPRD 18669648
S1507 Phosphorylation HPRD 20068231
S1559 Phosphorylation HPRD 18767875, 18669648, 17081983, ...20068231
S1565 Phosphorylation HPRD 17081983, 20068231
S1600 Phosphorylation HPRD 19651622, 18669648, 17081983
S1602 Phosphorylation HPRD 19664994, 18669648, 20058876, ...17081983
S1642 Phosphorylation HPRD 19651622, 19664994
S1645 Phosphorylation HPRD 19651622, 18669648, 19664994
S1647 Phosphorylation HPRD 19651622, 18767875, 18669648, ...19664994
T1743 Phosphorylation HPRD 17081983
S1750 Phosphorylation HPRD 18669648
S1876 Phosphorylation HPRD 19651622, 18669648, 19664994, ...20068231
T1884 Phosphorylation HPRD 20068231
S1929 Phosphorylation HPRD 19413330, 17081983, 19664994, ...19651622, 18669648, 18707149, 20068231
T1930 Phosphorylation HPRD 17322306, 18669648
S1932 Phosphorylation HPRD 19413330, 18669648, 19664994, ...17081983
T1943 Phosphorylation HPRD 18669648
T1947 Phosphorylation HPRD 18669648
S2212 Phosphorylation HPRD 20068231
S2345 Phosphorylation HPRD 20068231, 18452278
S2398 Phosphorylation HPRD 18669648
T2400 Phosphorylation HPRD 18669648
S2402 Phosphorylation HPRD 18669648
T2467 Phosphorylation HPRD 20068231
S2561 Phosphorylation HPRD 19651622, 18669648
S2563 Phosphorylation HPRD 19651622, 18767875, 18669648
S2567 Phosphorylation HPRD 19651622, 18767875, 18669648
S2703 Phosphorylation HPRD 18669648, 20068231
S2709 Phosphorylation HPRD 18669648, 20068231
S2728 Phosphorylation HPRD 19413330, 20058876, 16964243, ...18767875, 19664994, 19664995, 18452278, 18669648, 20068231
S2761 Phosphorylation HPRD 20068230
S2766 Phosphorylation HPRD 20068230
Site PTM Type PTM Enzyme Score Source PMID
T393 Phosphorylation HPRD 18669648
S395 Phosphorylation HPRD 18669648
S649 Phosphorylation HPRD 20068231
T784 Phosphorylation HPRD 18669648
S790 Phosphorylation HPRD 18669648, 20068231
S793 Phosphorylation HPRD 18669648
T797 Phosphorylation HPRD 18669648
T815 Phosphorylation HPRD 18669648
S981 Phosphorylation HPRD 18691976
S983 Phosphorylation HPRD 19413330, 16964243, 18767875, ...19664994, 19664995, 19651622, 18669648, 20068231
T1170 Phosphorylation HPRD 18669648
S1411 Phosphorylation HPRD 18669648, 20068231
S1492 Phosphorylation HPRD 18669648
S1507 Phosphorylation HPRD 20068231
S1559 Phosphorylation HPRD 18767875, 18669648, 17081983, ...20068231
S1565 Phosphorylation HPRD 17081983, 20068231
S1582 Phosphorylation PhosphoSitePlus
S1584 Phosphorylation PhosphoSitePlus
S1588 Phosphorylation PhosphoSitePlus
S1604 Phosphorylation HPRD 19651622, 18669648, 17081983
S1606 Phosphorylation HPRD 19664994, 18669648, 20058876, ...17081983
S1646 Phosphorylation HPRD 19651622, 19664994
S1649 Phosphorylation HPRD 19651622, 18669648, 19664994
S1651 Phosphorylation HPRD 19651622, 18767875, 18669648, ...19664994
T1747 Phosphorylation HPRD 17081983
S1754 Phosphorylation HPRD 18669648
S1880 Phosphorylation HPRD 19651622, 18669648, 19664994, ...20068231
T1888 Phosphorylation HPRD 20068231
S1933 Phosphorylation HPRD 19413330, 17081983, 19664994, ...19651622, 18669648, 18707149, 20068231
T1934 Phosphorylation HPRD 17322306, 18669648
S1936 Phosphorylation HPRD 19413330, 18669648, 19664994, ...17081983
T1947 Phosphorylation HPRD 18669648
T1951 Phosphorylation HPRD 18669648
S2216 Phosphorylation HPRD 20068231
S2349 Phosphorylation HPRD 20068231, 18452278
S2402 Phosphorylation HPRD 18669648
T2404 Phosphorylation HPRD 18669648
S2406 Phosphorylation HPRD 18669648
T2471 Phosphorylation HPRD 20068231
S2565 Phosphorylation HPRD 19651622, 18669648
S2567 Phosphorylation HPRD 19651622, 18767875, 18669648
S2571 Phosphorylation HPRD 19651622, 18767875, 18669648
S2707 Phosphorylation HPRD 18669648, 20068231
S2713 Phosphorylation HPRD 18669648, 20068231
S2732 Phosphorylation HPRD 19413330, 20058876, 16964243, ...18767875, 19664994, 19664995, 18452278, 18669648, 20068231
S2765 Phosphorylation HPRD 20068230
S2770 Phosphorylation HPRD 20068230
Site PTM Type PTM Enzyme Score Source PMID
T1929 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S395 Y395 Biomuta DOID:363 / uterine cancer [ tcga ]
S1226 N1226 Biomuta DOID:363 / uterine cancer [ cosmic ]
T1227 S1227 Biomuta DOID:10534 / stomach cancer [ tcga ]
T1385 S1385 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
S1507 I1507 Biomuta DOID:3571 / liver cancer [ icgc ]
S1647 * Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]
S1746 I1746 Biomuta DOID:2394 / ovarian cancer [ icgc, tcga ] DOID:2994 / germ cell cancer [ cosmic ]
S1750 I1750 Biomuta DOID:3571 / liver cancer [ icgc ]
S1837 F1837 Biomuta DOID:3070 / malignant glioma [ cosmic ]
S1849 I1849 Biomuta DOID:363 / uterine cancer [ tcga ]
S1857 * Biomuta DOID:9256 / colorectal cancer [ tcga ]
S1876 F1876 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
T1884 I1884 Biomuta DOID:2394 / ovarian cancer [ tcga ] DOID:2994 / germ cell cancer [ cosmic ]
T1887 S1887 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S1900 L1900 Biomuta DOID:363 / uterine cancer [ tcga ]
S1929 L1929 Biomuta DOID:1324 / lung cancer [ tcga ]
S1945 L1945 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S1945 P1945 Biomuta DOID:363 / uterine cancer [ icgc, tcga ]
S1977 I1977 Biomuta DOID:3571 / liver cancer [ icgc ]
S2237 N2237 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
T2411 A2411 Biomuta DOID:3571 / liver cancer [ icgc, tcga ] DOID:0070003 / blastoma [ cosmic ]
S2561 R2561 Biomuta DOID:0070003 / blastoma [ cosmic ]
S2733 N2733 Biomuta DOID:3070 / malignant glioma [ tcga ]
S2733 I2733 Biomuta DOID:363 / uterine cancer [ tcga ]
S2802 * Biomuta DOID:1612 / breast cancer [ icgc ] DOID:1324 / lung cancer [ cosmic ]