iPTMnet Report for Q12798 (CETN1)
Protein Information
| UniProt AC / UniProt ID | Q12798 / CETN1_HUMAN |
| Protein Name | Centrin-1 |
| Gene Name | Name: CETN1 Synonyms:CEN1,CETN; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q12798 |
| PRO Name | centrin-1 (human) |
| Definition | A centrin-1 that is encoded in the genome of human. |
| Short Label | hCETN1 |
| Category | organism-gene |
DAG ViewQ12798 (CETN1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S9 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K54 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K103 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K120 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K124 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K127 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T138 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 24918055 | ||
| S170 | Phosphorylation | P17612 (PRKACA) | score3 | HPRD phospho.ELM PhosphoSitePlus | 11279195 | |
| Y172 | Phosphorylation | score0 | RLIMS-P | 24918055 |
PTM-dependent PPI
|
PTM type | Substrate | Site | Interactant | Association type | Source | PMID |
|---|---|---|---|---|---|---|---|
| Phosphorylation | Q12798 (CETN1) | T138 | A8K8P3 (SFI1) | decreased_association | eFIP | 24918055 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K54 | R54 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] | |
| K103 | Q103 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S170 | C170 | Biomuta | DOID:1612 / breast cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] |
