iPTMnet Report for Q12797 (ASPH)
Protein Information
UniProt AC / UniProt ID | Q12797 / ASPH_HUMAN |
Protein Name | Aspartyl/asparaginyl beta-hydroxylase |
Gene Name | Name: ASPH Synonyms:BAH; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q12797 |
PRO Name | aspartyl/asparaginyl beta-hydroxylase (human) |
Definition | An aspartyl/asparaginyl beta-hydroxylase that is encoded in the genome of human. |
Short Label | hASPH |
Category | organism-gene |
Q12797 (ASPH) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K8 | Ubiquitination | score1 | PhosphoSitePlus | |||
S9 | Phosphorylation | score1 | PhosphoSitePlus | |||
S10 | Phosphorylation | score1 | PhosphoSitePlus | |||
S14 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
S15 | Phosphorylation | score1 | PhosphoSitePlus | |||
S16 | Phosphorylation | score1 | PhosphoSitePlus | |||
S18 | Phosphorylation | score1 | PhosphoSitePlus | |||
S20 | Phosphorylation | score1 | PhosphoSitePlus | |||
S22 | Phosphorylation | score1 | PhosphoSitePlus | |||
T23 | Phosphorylation | score1 | PhosphoSitePlus | |||
S24 | Phosphorylation | score1 | PhosphoSitePlus | |||
S27 | Phosphorylation | score1 | PhosphoSitePlus | |||
S28 | Phosphorylation | score1 | PhosphoSitePlus | |||
S29 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 15302935 | ||
T36 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y90 | Phosphorylation | score1 | PhosphoSitePlus | |||
K104 | Ubiquitination | score1 | PhosphoSitePlus | |||
K110 | Ubiquitination | score1 | PhosphoSitePlus | |||
T114 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
T128 | Phosphorylation | score1 | PhosphoSitePlus | |||
T176 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
S204 | Phosphorylation | score1 | PhosphoSitePlus | |||
T280 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
K323 | Acetylation | score1 | PhosphoSitePlus | |||
K336 | Acetylation | score1 | PhosphoSitePlus | |||
K350 | Ubiquitination | score1 | PhosphoSitePlus | |||
K370 | Acetylation | score1 | PhosphoSitePlus | |||
S374 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y405 | Phosphorylation | score1 | PhosphoSitePlus | |||
K420 | Ubiquitination | score1 | PhosphoSitePlus | |||
N452 | N-Glycosylation | score1 | GlyGen | 23090970, 29741879, 24190977 | ||
N458 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
Y464 | Phosphorylation | score1 | PhosphoSitePlus | |||
K474 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y477 | Phosphorylation | score1 | PhosphoSitePlus | |||
T484 | Phosphorylation | score1 | PhosphoSitePlus | |||
K499 | Acetylation | score1 | PhosphoSitePlus | |||
Y510 | Phosphorylation | score1 | PhosphoSitePlus | |||
K512 | Ubiquitination | score1 | PhosphoSitePlus | |||
S517 | Phosphorylation | score1 | PhosphoSitePlus | |||
T522 | Phosphorylation | score1 | PhosphoSitePlus | |||
K541 | Ubiquitination | score1 | PhosphoSitePlus | |||
K545 | Acetylation | score1 | PhosphoSitePlus | |||
K545 | Ubiquitination | score1 | PhosphoSitePlus | |||
T577 | Phosphorylation | score1 | PhosphoSitePlus | |||
K579 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y583 | Phosphorylation | score1 | PhosphoSitePlus | |||
K588 | Ubiquitination | score1 | PhosphoSitePlus | |||
K622 | Ubiquitination | score1 | PhosphoSitePlus | |||
K653 | Acetylation | score1 | PhosphoSitePlus | |||
N706 | N-Glycosylation | score1 | GlyGen | 24190977 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S9 | Phosphorylation | score0 | HPRD | 20068231, 20068230 | ||
S10 | Phosphorylation | score0 | HPRD | 20068231, 20068230 | ||
S13 | Phosphorylation | score0 | HPRD | 20068231 | ||
S22 | Phosphorylation | score0 | HPRD | 20068230 | ||
T23 | Phosphorylation | score0 | HPRD | 20068230 | ||
S24 | Phosphorylation | score0 | HPRD | 20068231, 20068230 | ||
S27 | Phosphorylation | score0 | HPRD | 20068230 | ||
S28 | Phosphorylation | score0 | HPRD | 19651622, 20068231, 20068230 | ||
S29 | Phosphorylation | score0 | HPRD | 19651622, 17924679, 15302935, ... |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S9 | Phosphorylation | score0 | HPRD | 20068231, 20068230 | ||
S10 | Phosphorylation | score0 | HPRD | 20068231, 20068230 | ||
S13 | Phosphorylation | score0 | HPRD | 20068231 | ||
S22 | Phosphorylation | score0 | HPRD | 20068230 | ||
T23 | Phosphorylation | score0 | HPRD | 20068230 | ||
S24 | Phosphorylation | score0 | HPRD | 20068231, 20068230 | ||
S27 | Phosphorylation | score0 | HPRD | 20068230 | ||
S28 | Phosphorylation | score0 | HPRD | 19651622, 20068231, 20068230 | ||
S29 | Phosphorylation | score0 | HPRD | 19651622, 17924679, 15302935, ... |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Y63 | Phosphorylation | score1 | PhosphoSitePlus | |||
S66 | Phosphorylation | score1 | PhosphoSitePlus | |||
K101 | Ubiquitination | score1 | PhosphoSitePlus | |||
K135 | Ubiquitination | score1 | PhosphoSitePlus | |||
K136 | Acetylation | score1 | PhosphoSitePlus | |||
K136 | Ubiquitination | score1 | PhosphoSitePlus | |||
K139 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S15 | N15 | Biomuta | DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ] | |
S24 | R24 | Biomuta | DOID:3963 / thyroid carcinoma [ cosmic, icgc ] | |
T128 | N128 | Biomuta | DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ] | |
K336 | T336 | Biomuta | DOID:9256 / colorectal cancer [ tcga ] | |
N452 | D452 | Biomuta | DOID:3070 / malignant glioma [ tcga ] | |
Y464 | * | Biomuta | DOID:3571 / liver cancer [ icgc ] | |
Y464 | C464 | Biomuta | DOID:363 / uterine cancer [ tcga ] DOID:9256 / colorectal cancer [ tcga ] | |
Y477 | F477 | Biomuta | DOID:3571 / liver cancer [ icgc, tcga ] DOID:0070003 / blastoma [ cosmic ] | |
K512 | N512 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S517 | F517 | Biomuta | DOID:1909 / melanoma [ icgc, tcga ] | |
K579 | N579 | Biomuta | DOID:1793 / pancreatic cancer [ tcga ] |