iPTMnet Report for Q12791 (KCNMA1)
Protein Information
| UniProt AC / UniProt ID | Q12791 / KCMA1_HUMAN |
| Protein Name | Calcium-activated potassium channel subunit alpha-1 |
| Gene Name | Name: KCNMA1 Synonyms:KCNMA,SLO; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q12791 |
| PRO Name | calcium-activated potassium channel subunit alpha-1 (human) |
| Definition | A calcium-activated potassium channel subunit alpha-1 that is encoded in the genome of human. |
| Short Label | hKCNMA1 |
| Category | organism-gene |
Q12791 (KCNMA1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S12 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S22 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S41 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S42 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S43 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S44 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S45 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S47 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S50 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S51 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S52 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S53 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S55 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S562 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S569 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T763 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S765 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S778 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N780 | N-Glycosylation | score1 | GlyGen | 29741879 | ||
| S782 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S811 | Phosphorylation | Q13976 (PRKG1) | score2 | neXtProt | 23407708 | |
| S978 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S992 | Phosphorylation | Q13976 (PRKG1) | score3 | neXtProt PhosphoSitePlus | 23407708 | |
| Y1086 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18083107 | ||
| S1146 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1149 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1152 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1188 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1195 | Phosphorylation | score1 | PRO | |||
| S1196 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1200 | Phosphorylation | P17252 (PRKCA) | score3 | PhosphoSitePlus Signor | 19592459 | |
| S1204 | Phosphorylation | Q13976 (PRKG1) | score2 | neXtProt | 23407708 | |
| S1205 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1208 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R1215 | Methylation | score1 | PhosphoSitePlus | |||
| Y1230 | Phosphorylation | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S704 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T705 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S707 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K710 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K711 | Ubiquitination | score1 | PhosphoSitePlus |
Proteoforms
| PRO ID (Short Label) | Sites | PTM Enzyme | Source | PMID | |
|---|---|---|---|---|---|
| PR:000048092 (hKCNMA1/Phos:1) | pS1195 | PRO |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S50 | Y50 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| S53 | F53 | Biomuta | [ cosmic ] DOID:1324 / lung cancer [ cosmic ] DOID:1115 / sarcoma [ icgc ] | |
| S562 | N562 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S569 | F569 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S569 | Y569 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc, tcga ] | |
| S704 | L704 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S704 | * | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
| S782 | A782 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
| S782 | L782 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S1195 | L1195 | Biomuta | DOID:1785 / pituitary cancer [ cosmic ] | |
| S1200 | N1200 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| S1208 | F1208 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| R1215 | Q1215 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
| Y1230 | H1230 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] |
DAG View