iPTMnet Report for Q10469 (MGAT2)
Protein Information
| UniProt AC / UniProt ID | Q10469 / MGAT2_HUMAN |
| Protein Name | Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase |
| Gene Name | Name: MGAT2 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q10469 |
| PRO Name | alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (human) |
| Definition | An alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase that is encoded in the genome of human. |
| Short Label | hMGAT2 |
| Category | organism-gene |
Q10469 (MGAT2) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S59 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 34725712, 25813380, 34019948, ... | ||
| S68 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S71 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S74 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| N86 | N-Glycosylation | score3 | GlyGen UniProt | 29666272 | ||
| S137 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K207 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K226 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y301 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K306 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S356 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S389 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T390 | O-Glycosylation | score1 | GlyGen | 30459171, 25813380 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K207 | N207 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] | |
| K226 | N226 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |
DAG View