Protein Information

Cytoscape View

UniProt AC / UniProt ID Q0VGL1 / LTOR4_HUMAN
Protein Name Ragulator complex protein LAMTOR4
Gene Name Name: LAMTOR4
Organism Homo sapiens (Human)

DAG View
PRO Name ragulator complex protein LAMTOR4 (human)
Definition A ragulator complex protein LAMTOR4 that is encoded in the genome of human.
Short Label hLAMTOR4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q0VGL1 (LAMTOR4) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
T2 Acetylation UniProt 19413330, 22814378, 25944712
T2 Phosphorylation HPRD 20068231
T6 Phosphorylation HPRD 20068231
K64 Ubiquitination PhosphoSitePlus
S67 Phosphorylation PhosphoSitePlus   RLIMS-P 31314152
K88 Ubiquitination PhosphoSitePlus

PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q0VGL1 (LAMTOR4) S67 Q6IAA8 (LAMTOR1) inhibited_association eFIP 31314152

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S67 C67 Biomuta DOID:5041 / esophageal cancer [ icgc ]
K88 * Biomuta DOID:363 / uterine cancer [ tcga ]