iPTMnet Report for Q09328 (MGAT5)
Protein Information
| UniProt AC / UniProt ID | Q09328 / MGT5A_HUMAN |
| Protein Name | Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A precursor |
| Gene Name | Name: MGAT5 Synonyms:GGNT5; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q09328 |
| PRO Name | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (human) |
| Definition | An alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A that is encoded in the genome of human. |
| Short Label | hMGAT5 |
| Category | organism-gene |
DAG ViewQ09328 (MGAT5) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T33 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
| T38 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
| K55 | Acetylation | score1 | PhosphoSitePlus | |||
| K55 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y57 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y80 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K84 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T121 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| C172 | Methylation | score1 | IEDB | 31844290 | ||
| T220 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y226 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S227 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T278 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N334 | N-Glycosylation | score2 | GlyGen | 15084511 | ||
| N433 | N-Glycosylation | score4 | GlyGen UniProt | 30140003, 15084511 | ||
| N447 | N-Glycosylation | score3 | GlyGen | 23090970, 15084511, 24190977 | ||
| Y452 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K462 | Acetylation | score1 | PhosphoSitePlus | |||
| K463 | Acetylation | score1 | PhosphoSitePlus | |||
| S544 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S545 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T548 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K554 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T556 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S712 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K55 | Q55 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| C172 | S172 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] | |
| Y226 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| Y226 | C226 | Biomuta | DOID:4362 / cervical cancer [ icgc ] | |
| N334 | S334 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
| S712 | G712 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] |
