iPTMnet Report for Q09327 (MGAT3)
Protein Information
| UniProt AC / UniProt ID | Q09327 / MGAT3_HUMAN |
| Protein Name | Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase |
| Gene Name | Name: MGAT3 Synonyms:GGNT3; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q09327 |
| PRO Name | beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase (human) |
| Definition | A beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase that is encoded in the genome of human. |
| Short Label | hMGAT3 |
| Category | organism-gene |
Q09327 (MGAT3) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S61 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| T72 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
| S76 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
| S87 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
| K123 | Acetylation | score1 | PhosphoSitePlus | |||
| N241 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| N259 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| Y264 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K489 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S61 | R61 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| T72 | I72 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S76 | F76 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
| K123 | N123 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
| N241 | D241 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] |
DAG View