iPTMnet Report for Q09327 (MGAT3)
Protein Information
UniProt AC / UniProt ID | Q09327 / MGAT3_HUMAN |
Protein Name | Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase |
Gene Name | Name: MGAT3 Synonyms:GGNT3; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q09327 |
PRO Name | beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase (human) |
Definition | A beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase that is encoded in the genome of human. |
Short Label | hMGAT3 |
Category | organism-gene |
Q09327 (MGAT3) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S61 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
T72 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
S76 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
S87 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
K123 | Acetylation | score1 | PhosphoSitePlus | |||
N241 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
N259 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
Y264 | Phosphorylation | score1 | PhosphoSitePlus | |||
K489 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S61 | R61 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
T72 | I72 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S76 | F76 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
K123 | N123 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
N241 | D241 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] |