iPTMnet Report for Q09028 (RBBP4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q09028 / RBBP4_HUMAN
Protein Name Histone-binding protein RBBP4
Gene Name Name: RBBP4
Synonyms:RBAP48;
Organism Homo sapiens (Human)

PRO ID PR:Q09028
DAG View
PRO Name histone-binding protein RBBP4 (human)
Definition A histone-binding protein RBBP4 that is encoded in the genome of human.
Short Label hRBBP4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q09028 (RBBP4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22814378, 22223895
K4 Acetylation PhosphoSitePlus   UniProt 19608861
K4 Ubiquitination PhosphoSitePlus
R15 Methylation PhosphoSitePlus
Y21 Phosphorylation PhosphoSitePlus
K22 Acetylation PhosphoSitePlus
K22 Sumoylation PhosphoSitePlus
K22 Ubiquitination PhosphoSitePlus
K26 Ubiquitination PhosphoSitePlus
R55 Methylation PhosphoSitePlus
K102 Ubiquitination PhosphoSitePlus
S110 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
S112 Phosphorylation PhosphoSitePlus
C138 Methylation IEDB 31844290
K143 Ubiquitination PhosphoSitePlus
T144 Phosphorylation PhosphoSitePlus
S146 Phosphorylation PhosphoSitePlus
S147 Phosphorylation PhosphoSitePlus
T155 Phosphorylation PhosphoSitePlus
K156 Ubiquitination PhosphoSitePlus
S159 Phosphorylation PhosphoSitePlus
K160 Acetylation PhosphoSitePlus
K160 Sumoylation PhosphoSitePlus
K160 Ubiquitination PhosphoSitePlus
C167 Methylation IEDB 31844290
C167 S-Nitrosylation dbSNO 26338901
K178 Ubiquitination PhosphoSitePlus
S190 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...26853435, 29351928, 34019948, 20305658, 32119511, 28510447, 34229054
C203 Methylation IEDB 31844290
K215 Acetylation PhosphoSitePlus
K220 Ubiquitination PhosphoSitePlus
R258 Methylation PhosphoSitePlus
K264 Ubiquitination PhosphoSitePlus
C278 Methylation IEDB 31844290
T297 Phosphorylation PhosphoSitePlus
R304 Methylation PhosphoSitePlus
K307 Sumoylation PhosphoSitePlus
K309 Ubiquitination PhosphoSitePlus
K317 Ubiquitination PhosphoSitePlus
S326 Phosphorylation PhosphoSitePlus
R341 Methylation PhosphoSitePlus
S348 Phosphorylation PhosphoSitePlus
K349 Ubiquitination PhosphoSitePlus
S355 Phosphorylation PhosphoSitePlus   UniProt 23186163
T374 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S146 Phosphorylation HPRD 19413330
S348 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R15 L15 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R55 I55 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S112 I112 Biomuta DOID:3571 / liver cancer [ cosmic ]
K215 R215 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
R304 I304 Biomuta DOID:363 / uterine cancer [ icgc ]
K309 M309 Biomuta DOID:1324 / lung cancer [ cosmic ]
S348 C348 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S355 C355 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]