iPTMnet Report for Q09019 (DMWD)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q09019 / DMWD_HUMAN
Protein Name Dystrophia myotonica WD repeat-containing protein
Gene Name Name: DMWD
Synonyms:DM9;
Organism Homo sapiens (Human)

PRO ID PR:Q09019
DAG View
PRO Name dystrophia myotonica WD repeat-containing protein (human)
Definition A dystrophia myotonica WD repeat-containing protein that is encoded in the genome of human.
Short Label hDMWD
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q09019 (DMWD) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378
S148 Phosphorylation PhosphoSitePlus
K153 Ubiquitination PhosphoSitePlus
K157 Ubiquitination PhosphoSitePlus
K199 Ubiquitination PhosphoSitePlus
K203 Ubiquitination PhosphoSitePlus
Y266 Phosphorylation PhosphoSitePlus
K269 Ubiquitination PhosphoSitePlus
K279 Ubiquitination PhosphoSitePlus
R396 Methylation PhosphoSitePlus
S397 Phosphorylation PhosphoSitePlus
S419 Phosphorylation PhosphoSitePlus
T459 Phosphorylation PhosphoSitePlus
T461 Phosphorylation PhosphoSitePlus
T465 Phosphorylation HPRD   PhosphoSitePlus 18452278
T468 Phosphorylation PhosphoSitePlus
T469 Phosphorylation HPRD   PhosphoSitePlus 18452278
R477 Methylation PhosphoSitePlus
S491 Phosphorylation PhosphoSitePlus
S493 Phosphorylation PhosphoSitePlus
S495 Phosphorylation PhosphoSitePlus   UniProt 23186163
T516 Phosphorylation PhosphoSitePlus
T525 Phosphorylation PhosphoSitePlus
K538 Acetylation PhosphoSitePlus
S545 Phosphorylation HPRD   PhosphoSitePlus 15302935
S550 Phosphorylation PhosphoSitePlus
R551 Methylation PhosphoSitePlus
S554 Phosphorylation PhosphoSitePlus
K563 Ubiquitination PhosphoSitePlus
K577 Ubiquitination PhosphoSitePlus
C584 Methylation IEDB 31844290
S652 Phosphorylation PhosphoSitePlus
K655 Ubiquitination PhosphoSitePlus
S662 Phosphorylation PhosphoSitePlus
S663 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R396 Q396 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S419 F419 Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
S495 C495 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
K577 N577 Biomuta DOID:363 / uterine cancer [ icgc ]
C584 F584 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S663 F663 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]