Protein Information

Cytoscape View


UniProt AC / UniProt ID Q09013 / DMPK_HUMAN
Protein Name Myotonin-protein kinase
Gene Name Name: DMPK
Synonyms:DM1PK,MDPK;
Organism Homo sapiens (Human)

PRO ID PR:Q09013
DAG View
PRO Name myotonin-protein kinase (human)
Definition A myotonin-protein kinase that is encoded in the genome of human.
Short Label hDMPK
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q09013 (DMPK) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus
K75 Ubiquitination PhosphoSitePlus
K197 Ubiquitination PhosphoSitePlus
T533 Phosphorylation PhosphoSitePlus
T536 Phosphorylation PhosphoSitePlus
S540 Phosphorylation PhosphoSitePlus
R579 Methylation PhosphoSitePlus


Q09013 (DMPK) as PTM Enzyme



Substrate Site Score Source PMID
O14974-1 (PPP1R12A) T696 HPRD   neXtProt 11287000, 18212344, 18767875, ...11931630, 12600888, 12220642, 18669648, 10601309, 18077418
P11831 (SRF) T159 PhosphoSitePlus 12809504
P26678 (PLN) S16 neXtProt 15598648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K75 R75 Biomuta DOID:1909 / melanoma [ cosmic ]
T536 M536 Biomuta DOID:363 / uterine cancer [ tcga ]