iPTMnet Report for Q08ER8 (ZNF543)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q08ER8 / ZN543_HUMAN
Protein Name Zinc finger protein 543
Gene Name Name: ZNF543
Organism Homo sapiens (Human)

PRO ID PR:Q08ER8
DAG View
PRO Name zinc finger protein 543 (human)
Definition A zinc finger protein 543 that is encoded in the genome of human.
Short Label hZNF543
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q08ER8 (ZNF543) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K72 Ubiquitination PhosphoSitePlus
S77 Phosphorylation PhosphoSitePlus
K85 Ubiquitination PhosphoSitePlus
K122 Ubiquitination PhosphoSitePlus
C164 Methylation IEDB 31844290
T165 Phosphorylation PhosphoSitePlus
K166 Ubiquitination PhosphoSitePlus
T168 Phosphorylation PhosphoSitePlus
K170 Ubiquitination PhosphoSitePlus
K200 Sumoylation PhosphoSitePlus
K210 Sumoylation PhosphoSitePlus
K210 Ubiquitination PhosphoSitePlus
K225 Ubiquitination PhosphoSitePlus
K234 Ubiquitination PhosphoSitePlus
T250 Phosphorylation PhosphoSitePlus
K253 Ubiquitination PhosphoSitePlus
S278 Phosphorylation PhosphoSitePlus
Y283 Phosphorylation PhosphoSitePlus
K290 Acetylation PhosphoSitePlus
T293 Phosphorylation PhosphoSitePlus
T306 Phosphorylation PhosphoSitePlus
K309 Sumoylation PhosphoSitePlus
K309 Ubiquitination PhosphoSitePlus
K314 Ubiquitination PhosphoSitePlus
T334 Phosphorylation PhosphoSitePlus
K337 Ubiquitination PhosphoSitePlus
K365 Ubiquitination PhosphoSitePlus
T390 Phosphorylation PhosphoSitePlus
K393 Ubiquitination PhosphoSitePlus
T418 Phosphorylation PhosphoSitePlus
S426 Phosphorylation PhosphoSitePlus
T444 Phosphorylation PhosphoSitePlus
T446 Phosphorylation PhosphoSitePlus
K449 Ubiquitination PhosphoSitePlus
K454 Sumoylation PhosphoSitePlus
K454 Ubiquitination PhosphoSitePlus
S471 Phosphorylation PhosphoSitePlus
T474 Phosphorylation PhosphoSitePlus
K477 Ubiquitination PhosphoSitePlus
Y479 Phosphorylation PhosphoSitePlus
K486 Sumoylation PhosphoSitePlus
K486 Ubiquitination PhosphoSitePlus
T502 Phosphorylation PhosphoSitePlus
K505 Ubiquitination PhosphoSitePlus
K514 Ubiquitination PhosphoSitePlus
T530 Phosphorylation PhosphoSitePlus
K533 Ubiquitination PhosphoSitePlus
Y535 Phosphorylation PhosphoSitePlus
S538 Phosphorylation PhosphoSitePlus
K542 Sumoylation PhosphoSitePlus
K542 Ubiquitination PhosphoSitePlus
T563 Phosphorylation PhosphoSitePlus
T574 Phosphorylation PhosphoSitePlus
S578 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K122 N122 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
K170 R170 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K200 R200 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K225 N225 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T250 N250 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T293 I293 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T334 M334 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K393 T393 Biomuta DOID:5158 / pleural cancer [ cosmic ]
S426 G426 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K449 N449 Biomuta DOID:9256 / colorectal cancer [ icgc ]
T563 N563 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
T563 I563 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T574 I574 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S578 L578 Biomuta DOID:3571 / liver cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]