iPTMnet Report for Q08AH3 (ACSM2A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q08AH3 / ACS2A_HUMAN
Protein Name Acyl-coenzyme A synthetase ACSM2A, mitochondrial precursor
Gene Name Name: ACSM2A
Synonyms:ACSM2,MACS2;
Organism Homo sapiens (Human)

PRO ID PR:Q08AH3
DAG View
PRO Name acyl-coenzyme A synthetase ACSM2A, mitochondrial (human)
Definition An acyl-coenzyme A synthetase ACSM2A, mitochondrial that is encoded in the genome of human.
Short Label hACSM2A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q08AH3 (ACSM2A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K75 Acetylation PhosphoSitePlus
S172 Phosphorylation PhosphoSitePlus
K195 Acetylation PhosphoSitePlus
K298 Acetylation PhosphoSitePlus
Y303 Phosphorylation PhosphoSitePlus
S307 Phosphorylation PhosphoSitePlus
S373 Phosphorylation PhosphoSitePlus
S517 Phosphorylation PhosphoSitePlus
Y538 Phosphorylation PhosphoSitePlus
Y540 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K195 T195 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]
K195 R195 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S517 F517 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y538 F538 Biomuta DOID:3571 / liver cancer [ cosmic ]