iPTMnet Report for Q08AF3 (SLFN5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q08AF3 / SLFN5_HUMAN
Protein Name Schlafen family member 5
Gene Name Name: SLFN5
Organism Homo sapiens (Human)

PRO ID PR:Q08AF3
DAG View
PRO Name Schlafen family member 5 (human)
Definition A Schlafen family member 5 that is encoded in the genome of human.
Short Label hSLFN5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q08AF3 (SLFN5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K20 Ubiquitination PhosphoSitePlus
K38 Ubiquitination PhosphoSitePlus
K59 Ubiquitination PhosphoSitePlus
K65 Ubiquitination PhosphoSitePlus
K88 Ubiquitination PhosphoSitePlus
T123 Phosphorylation PhosphoSitePlus
K138 Ubiquitination PhosphoSitePlus
C236 Methylation IEDB 31844290
K245 Ubiquitination PhosphoSitePlus
K260 Ubiquitination PhosphoSitePlus
K261 Ubiquitination PhosphoSitePlus
K286 Ubiquitination PhosphoSitePlus
K300 Ubiquitination PhosphoSitePlus
K316 Ubiquitination PhosphoSitePlus
K365 Ubiquitination PhosphoSitePlus
K371 Ubiquitination PhosphoSitePlus
Y387 Phosphorylation PhosphoSitePlus
Y393 Phosphorylation PhosphoSitePlus
K394 Ubiquitination PhosphoSitePlus
K401 Ubiquitination PhosphoSitePlus
K481 Ubiquitination PhosphoSitePlus
K559 Ubiquitination PhosphoSitePlus
K566 Ubiquitination PhosphoSitePlus
T571 Phosphorylation IEDB 35494241
K584 Ubiquitination PhosphoSitePlus
C601 Methylation IEDB 31844290
K616 Ubiquitination PhosphoSitePlus
K617 Ubiquitination PhosphoSitePlus
S620 O-Glycosylation GlyGen 27655845, 29351928
K623 Methylation PhosphoSitePlus
K623 Ubiquitination PhosphoSitePlus
K624 Methylation PhosphoSitePlus
K624 Ubiquitination PhosphoSitePlus
K637 Ubiquitination PhosphoSitePlus
T656 O-Glycosylation GlyGen 27655845, 29351928
K664 Ubiquitination PhosphoSitePlus
K666 Ubiquitination PhosphoSitePlus
K796 Ubiquitination PhosphoSitePlus
S817 Phosphorylation PhosphoSitePlus
K888 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T123 A123 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
C236 * Biomuta DOID:363 / uterine cancer [ cosmic ]
K616 N616 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K617 N617 Biomuta DOID:1612 / breast cancer [ cosmic ]
K664 R664 Biomuta DOID:1324 / lung cancer [ cosmic ]
K664 N664 Biomuta DOID:3571 / liver cancer [ cosmic ]
K796 T796 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]