iPTMnet Report for Q08828 (ADCY1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q08828 / ADCY1_HUMAN
Protein Name Adenylate cyclase type 1
Gene Name Name: ADCY1
Organism Homo sapiens (Human)

PRO ID PR:Q08828
DAG View
PRO Name adenylate cyclase type 1 (human)
Definition An adenylate cyclase type 1 that is encoded in the genome of human.
Short Label hADCY1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q08828 (ADCY1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y52 Phosphorylation PhosphoSitePlus
T53 Phosphorylation HPRD   PhosphoSitePlus 18452278
T61 Phosphorylation HPRD   PhosphoSitePlus 18452278
S69 Phosphorylation HPRD   PhosphoSitePlus 18452278
S248 Phosphorylation PhosphoSitePlus
K293 Ubiquitination PhosphoSitePlus
Y416 Phosphorylation PhosphoSitePlus
S551 Phosphorylation PhosphoSitePlus
S924 Phosphorylation PhosphoSitePlus
Y926 Phosphorylation PhosphoSitePlus
T935 Phosphorylation PhosphoSitePlus
S936 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y416 H416 Biomuta DOID:1319 / brain cancer [ cosmic ]
S551 F551 Biomuta DOID:4159 / skin cancer [ cosmic ]
S924 R924 Biomuta DOID:4159 / skin cancer [ cosmic ]
S924 I924 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T935 N935 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S936 L936 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S936 * Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]