iPTMnet Report for Q08629 (SPOCK1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q08629 / TICN1_HUMAN
Protein Name Testican-1 precursor
Gene Name Name: SPOCK1
Synonyms:SPOCK,TIC1,TICN1;
Organism Homo sapiens (Human)

PRO ID PR:Q08629
DAG View
PRO Name testican-1 (human)
Definition A testican-1 that is encoded in the genome of human.
Short Label hSPOCK1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q08629 (SPOCK1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y65 O-Glycosylation GlyGen 23584533, 25813380
Y65 Phosphorylation PhosphoSitePlus
K118 Acetylation PhosphoSitePlus
K119 Acetylation PhosphoSitePlus
S131 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S131 Phosphorylation PhosphoSitePlus
S144 Phosphorylation PhosphoSitePlus
S150 Phosphorylation PhosphoSitePlus
K226 Ubiquitination PhosphoSitePlus
T228 O-Glycosylation GlyGen   PhosphoSitePlus   UniProt 23584533, 23234360
S248 Phosphorylation PhosphoSitePlus
N286 N-Glycosylation GlyGen 23090970, 24190977
T346 Phosphorylation PhosphoSitePlus
S351 Phosphorylation PhosphoSitePlus
T352 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S131 L131 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T228 N228 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S248 F248 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
N286 Y286 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S351 I351 Biomuta DOID:363 / uterine cancer [ icgc ]
T352 M352 Biomuta DOID:1324 / lung cancer [ cosmic ]