iPTMnet Report for Q08554 (DSC1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q08554 / DSC1_HUMAN
Protein Name Desmocollin-1 precursor
Gene Name Name: DSC1
Synonyms:CDHF1;
Organism Homo sapiens (Human)

PRO ID PR:Q08554
DAG View
PRO Name desmocollin-1 (human)
Definition A desmocollin-1 that is encoded in the genome of human.
Short Label hDSC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q08554 (DSC1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S60 Phosphorylation PhosphoSitePlus
S86 Phosphorylation PhosphoSitePlus
Y211 Phosphorylation PhosphoSitePlus
T385 Phosphorylation PhosphoSitePlus   UniProt 17487921
S443 Phosphorylation PhosphoSitePlus
Y639 Phosphorylation PhosphoSitePlus
Y642 Phosphorylation PhosphoSitePlus
T657 Phosphorylation PhosphoSitePlus
K676 Acetylation PhosphoSitePlus
Y846 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T385 Phosphorylation HPRD 17924679, 18452278
Site PTM Type PTM Enzyme Score Source PMID
T385 Phosphorylation HPRD 17924679, 18452278
S831 Phosphorylation PhosphoSitePlus
T836 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S443 F443 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T657 K657 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
K676 N676 Biomuta DOID:1319 / brain cancer [ icgc ] DOID:2531 / hematologic cancer [ cosmic ]
S831 F831 Biomuta DOID:4159 / skin cancer [ icgc ]