iPTMnet Report for Q08397 (LOXL1)
Protein Information
UniProt AC / UniProt ID | Q08397 / LOXL1_HUMAN |
Protein Name | Lysyl oxidase homolog 1 precursor |
Gene Name | Name: LOXL1 Synonyms:LOXL; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q08397 |
PRO Name | lysyl oxidase homolog 1 (human) |
Definition | A lysyl oxidase homolog 1 that is encoded in the genome of human. |
Short Label | hLOXL1 |
Category | organism-gene |
Q08397 (LOXL1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S99 | Phosphorylation | score1 | PhosphoSitePlus | |||
R141 | Methylation | score1 | PhosphoSitePlus | |||
T197 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y226 | Phosphorylation | score1 | PhosphoSitePlus | |||
T283 | O-Glycosylation | score1 | GlyGen | 30459171 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
R141 | L141 | Biomuta | [ cosmic ] DOID:1319 / brain cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic, icgc ] | |
Y226 | S226 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] |