iPTMnet Report for Q08380 (LGALS3BP)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q08380 / LG3BP_HUMAN
Protein Name Galectin-3-binding protein precursor
Gene Name Name: LGALS3BP
Synonyms:M2BP;
Organism Homo sapiens (Human)

PRO ID PR:Q08380
DAG View
PRO Name galectin-3-binding protein (human)
Definition A galectin-3-binding protein that is encoded in the genome of human.
Short Label hLGALS3BP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q08380 (LGALS3BP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y41 Phosphorylation PhosphoSitePlus
N69 N-Glycosylation GlyGen   UniProt 16335952, 34089345, 32125861, ...19159218, 24190977, 23090970, 26791533, 29391424, 15084671, 19139490, 16740002, 18780401, 9501082, 29741879, 29671580
T71 O-Glycosylation GlyGen 32574038
K110 Ubiquitination PhosphoSitePlus
N125 N-Glycosylation GlyGen   UniProt 16335952, 34089345, 19159218, ...24190977, 23090970, 29741879
C153 Methylation IEDB 31844290
N192 N-Glycosylation GlyGen   UniProt 16335952, 23090970, 29391424, ...19159218, 24190977
S223 Phosphorylation IEDB 35494241
K229 Ubiquitination PhosphoSitePlus
S256 Phosphorylation PhosphoSitePlus
N398 N-Glycosylation GlyGen   UniProt 16335952, 34089345, 32125861, ...19159218, 24190977, 23090970, 29391424, 19139490, 16740002, 29741879, 29671580
K405 Ubiquitination PhosphoSitePlus
S411 Phosphorylation PhosphoSitePlus
T413 O-Glycosylation GlyGen 30459171
T413 Phosphorylation PhosphoSitePlus
S415 Phosphorylation PhosphoSitePlus
K427 Ubiquitination PhosphoSitePlus
S428 Phosphorylation PhosphoSitePlus
Y432 Phosphorylation PhosphoSitePlus
S434 Phosphorylation PhosphoSitePlus
K441 Ubiquitination PhosphoSitePlus
S443 Phosphorylation PhosphoSitePlus
S444 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S444 Phosphorylation PhosphoSitePlus
Y446 Phosphorylation PhosphoSitePlus
Y458 Phosphorylation PhosphoSitePlus
T463 Phosphorylation PhosphoSitePlus
K474 Ubiquitination PhosphoSitePlus
T550 O-Glycosylation GlyGen 23301498, 28411811, 34725712, ...30397120, 32574038, 21526146, 33214551, 34019948, 28510447, 28657654
N551 N-Glycosylation GlyGen   UniProt 16335952, 34089345, 32125861, ...19159218, 24190977, 23090970, 29391424, 19139490, 16740002, 18780401, 29741879, 29671580
K554 Ubiquitination PhosphoSitePlus
N580 N-Glycosylation GlyGen   UniProt 16335952, 24190977, 23090970, ...19139490, 16740002, 29741879
Site PTM Type PTM Enzyme Score Source PMID
N69 N-Glycosylation PRO 26791533, 29671580
N398 N-Glycosylation PRO 29671580
N551 N-Glycosylation PRO 29671580


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N125 S125 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S256 L256 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S411 L411 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S434 F434 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
Y458 H458 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
N551 K551 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
N580 S580 Biomuta DOID:1324 / lung cancer [ cosmic ]