iPTMnet Report for Q08257 (CRYZ)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q08257 / QOR_HUMAN
Protein Name Quinone oxidoreductase
Gene Name Name: CRYZ
Organism Homo sapiens (Human)

PRO ID PR:Q08257
DAG View
PRO Name quinone oxidoreductase (human)
Definition A quinone oxidoreductase that is encoded in the genome of human.
Short Label hCRYZ
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q08257 (CRYZ) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378
K6 Acetylation PhosphoSitePlus
K6 Ubiquitination PhosphoSitePlus
K23 Acetylation PhosphoSitePlus   UniProt 19608861
K23 Ubiquitination PhosphoSitePlus
S26 Phosphorylation PhosphoSitePlus
K34 Ubiquitination PhosphoSitePlus
C45 S-Nitrosylation dbSNO 24105792
T52 Phosphorylation PhosphoSitePlus
Y53 Phosphorylation PhosphoSitePlus
K62 Ubiquitination PhosphoSitePlus
K88 Acetylation PhosphoSitePlus
K88 Ubiquitination PhosphoSitePlus
K89 Acetylation PhosphoSitePlus
T95 Phosphorylation PhosphoSitePlus
S96 Phosphorylation PhosphoSitePlus
S97 Phosphorylation PhosphoSitePlus
T98 Phosphorylation PhosphoSitePlus
Y103 Phosphorylation PhosphoSitePlus
Y106 Phosphorylation PhosphoSitePlus
K120 Ubiquitination PhosphoSitePlus
Y133 Phosphorylation PhosphoSitePlus
T135 Phosphorylation PhosphoSitePlus
Y137 Phosphorylation PhosphoSitePlus
C166 Methylation IEDB 31844290
K175 Ubiquitination PhosphoSitePlus
K187 Ubiquitination PhosphoSitePlus
K208 Acetylation PhosphoSitePlus
K208 Ubiquitination PhosphoSitePlus
K211 Acetylation PhosphoSitePlus
S248 Phosphorylation PhosphoSitePlus   UniProt 21406692
S264 Phosphorylation PhosphoSitePlus
S319 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S248 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 V2 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ]
K88 E88 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K88 N88 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K89 N89 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T98 K98 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S264 L264 Biomuta DOID:1725 / peritoneum cancer [ cosmic ]
S319 N319 Biomuta DOID:2021 / placenta cancer [ cosmic ]
S319 R319 Biomuta DOID:5041 / esophageal cancer [ cosmic ]