iPTMnet Report for Q08188 (TGM3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q08188 / TGM3_HUMAN
Protein Name Protein-glutamine gamma-glutamyltransferase E precursor
Gene Name Name: TGM3
Organism Homo sapiens (Human)

PRO ID PR:Q08188
DAG View
PRO Name protein-glutamine gamma-glutamyltransferase E (human)
Definition A protein-glutamine gamma-glutamyltransferase E that is encoded in the genome of human.
Short Label hTGM3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q08188 (TGM3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y111 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19651622, 19690332
T112 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19651622, 19690332
S119 Phosphorylation HPRD   PhosphoSitePlus 19651622
S124 Phosphorylation HPRD 19651622
S125 Phosphorylation PhosphoSitePlus
S221 Phosphorylation PhosphoSitePlus
T242 Phosphorylation PhosphoSitePlus
S263 Phosphorylation PhosphoSitePlus
S266 Phosphorylation PhosphoSitePlus
Y313 Phosphorylation PhosphoSitePlus
Y440 Phosphorylation PhosphoSitePlus
Y442 Phosphorylation PhosphoSitePlus
K497 Acetylation PhosphoSitePlus
K565 Acetylation PhosphoSitePlus
K577 Acetylation PhosphoSitePlus
S635 Phosphorylation PhosphoSitePlus
S664 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y111 * Biomuta DOID:363 / uterine cancer [ cosmic ]
S124 F124 Biomuta DOID:4159 / skin cancer [ cosmic ]
S124 Y124 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S221 N221 Biomuta DOID:1324 / lung cancer [ cosmic ]
S263 Y263 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S263 F263 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:4362 / cervical cancer [ cosmic, icgc ]
S263 A263 Biomuta DOID:363 / uterine cancer [ icgc ]
S266 I266 Biomuta DOID:1324 / lung cancer [ cosmic ]
K565 R565 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]