iPTMnet Report for Q07869 (PPARA)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q07869 / PPARA_HUMAN
Protein Name Peroxisome proliferator-activated receptor alpha
Gene Name Name: PPARA
Synonyms:NR1C1,PPAR;
Organism Homo sapiens (Human)

PRO ID PR:Q07869
DAG View
PRO Name peroxisome proliferator-activated receptor alpha (human)
Definition A peroxisome proliferator-activated receptor alpha that is encoded in the genome of human.
Short Label hPPARA
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q07869 (PPARA) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S6 Phosphorylation PhosphoSitePlus
S12 Phosphorylation P28482 (MAPK1) , P27361 (MAPK3) phospho.ELM   PhosphoSitePlus   Signor 10187842
S21 Phosphorylation P27361 (MAPK3) , P28482 (MAPK1) phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor 22619672, 23634230, 10187842, ...21525007
S45 Phosphorylation PhosphoSitePlus
S179 Phosphorylation P05771-2 (PRKCB) , P17252 (PRKCA) PhosphoSitePlus   RLIMS-P 15131257
K185 Sumoylation PhosphoSitePlus
S230 Phosphorylation P05771-2 (PRKCB) , P17252 (PRKCA) PhosphoSitePlus   RLIMS-P 15131257
S280 Phosphorylation RLIMS-P 30745182
Site PTM Type PTM Enzyme Score Source PMID
S12 Phosphorylation P27361 (MAPK3) , P28482 (MAPK1) HPRD 10187842
S21 Phosphorylation P27361 (MAPK3) , P28482 (MAPK1) HPRD 10187842


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q09472 (EP300) S89 Q07869 (PPARA) unknown eFIP 26983400


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S45 I45 Biomuta DOID:1115 / sarcoma [ tcga ]