iPTMnet Report for Q07065 (CKAP4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q07065 / CKAP4_HUMAN
Protein Name Cytoskeleton-associated protein 4
Gene Name Name: CKAP4
Organism Homo sapiens (Human)

PRO ID PR:Q07065
DAG View
PRO Name cytoskeleton-associated protein 4 (human)
Definition A cytoskeleton-associated protein 4 that is encoded in the genome of human.
Short Label hCKAP4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q07065 (CKAP4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 22536245, 15703217
S9 Phosphorylation PhosphoSitePlus
S17 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 17287340, 17081983, 19651622, ...15703217, 22536245, 20068231
S19 Phosphorylation HPRD   PhosphoSitePlus   RLIMS-P   UniProt 17081983, 19651622, 15703217, ...22536245, 20068231
K21 Ubiquitination PhosphoSitePlus
S26 O-Glycosylation GlyGen 34846842, 33214551, 26374642, ...34725712, 26853435, 34019948, 33465208
S26 Phosphorylation PhosphoSitePlus
K78 Ubiquitination PhosphoSitePlus
C100 S-Nitrosylation dbSNO 2212679, 22126794, 22178444, ...26338901, 20140087
S101 Phosphorylation PhosphoSitePlus
S140 Phosphorylation PhosphoSitePlus
S145 Phosphorylation PhosphoSitePlus
K188 Ubiquitination PhosphoSitePlus
S195 Phosphorylation PhosphoSitePlus
S198 Phosphorylation PhosphoSitePlus
K206 Ubiquitination PhosphoSitePlus
K213 Ubiquitination PhosphoSitePlus
K223 Ubiquitination PhosphoSitePlus
T231 Phosphorylation HPRD   PhosphoSitePlus 18578522
S232 Phosphorylation PhosphoSitePlus   UniProt 26091039
T236 Phosphorylation PhosphoSitePlus
N249 N-Glycosylation GlyGen 24190977
N251 N-Glycosylation GlyGen 24190977
K264 Methylation PhosphoSitePlus
K270 Acetylation PhosphoSitePlus
K283 Ubiquitination PhosphoSitePlus
K287 Ubiquitination PhosphoSitePlus
K301 Ubiquitination PhosphoSitePlus
S312 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648
T313 Phosphorylation PhosphoSitePlus
T316 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
Y322 Phosphorylation PhosphoSitePlus
T323 Phosphorylation PhosphoSitePlus
S330 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
K332 Acetylation PhosphoSitePlus
K355 Ubiquitination PhosphoSitePlus
K405 Ubiquitination PhosphoSitePlus
S427 Phosphorylation HPRD   PhosphoSitePlus 20068231
S436 Phosphorylation PhosphoSitePlus
S460 Phosphorylation HPRD   PhosphoSitePlus 20166139, 18578522
S461 Phosphorylation HPRD   PhosphoSitePlus 18578522
K490 Acetylation PhosphoSitePlus
K490 Ubiquitination PhosphoSitePlus
S492 Phosphorylation HPRD   PhosphoSitePlus 20068231
T499 O-Glycosylation GlyGen 25813380
S502 O-Glycosylation GlyGen 34846842, 33214551, 26374642, ...34725712, 26853435, 34019948, 33465208
T512 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S515 Phosphorylation PhosphoSitePlus
S534 Phosphorylation HPRD   PhosphoSitePlus 20068230
S535 Phosphorylation HPRD   PhosphoSitePlus 20068230
K540 Ubiquitination PhosphoSitePlus
K551 Methylation PhosphoSitePlus
K551 Ubiquitination PhosphoSitePlus
Y563 Phosphorylation PhosphoSitePlus
S576 Phosphorylation PhosphoSitePlus
K578 Ubiquitination PhosphoSitePlus
R590 Methylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S26 L26 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K188 R188 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S195 R195 Biomuta DOID:184 / bone cancer [ cosmic ]
T231 M231 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ]
T236 K236 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S427 F427 Biomuta DOID:1324 / lung cancer [ cosmic ]
S460 P460 Biomuta DOID:363 / uterine cancer [ icgc ]
T512 S512 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R590 S590 Biomuta DOID:3571 / liver cancer [ cosmic ]