iPTMnet Report for Q07020 (RPL18)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q07020 / RL18_HUMAN
Protein Name Large ribosomal subunit protein eL18
Gene Name Name: RPL18
Organism Homo sapiens (Human)

PRO ID PR:Q07020
DAG View
PRO Name 60S ribosomal protein L18 (human)
Definition A 60S ribosomal protein L18 that is encoded in the genome of human.
Short Label hRPL18
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q07020 (RPL18) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R6 Methylation PhosphoSitePlus
R26 Methylation PhosphoSitePlus
K30 Acetylation PhosphoSitePlus
K30 Ubiquitination PhosphoSitePlus
T39 O-Glycosylation GlyGen 33214551, 34725712, 35138101, ...32522876, 34019948, 35083852, 32119511, 36580660, 28510447, 22121020, 33465208
T39 Phosphorylation PhosphoSitePlus
S41 O-Glycosylation GlyGen 33465208
S41 Phosphorylation PhosphoSitePlus
T42 O-Glycosylation GlyGen 33465208
T42 Phosphorylation PhosphoSitePlus
K49 Ubiquitination PhosphoSitePlus
S62 Phosphorylation PhosphoSitePlus
S64 Phosphorylation PhosphoSitePlus
R65 Methylation PhosphoSitePlus
K78 Ubiquitination PhosphoSitePlus
T79 Phosphorylation PhosphoSitePlus
T85 Phosphorylation PhosphoSitePlus
T87 Phosphorylation PhosphoSitePlus
R91 Methylation PhosphoSitePlus
K97 Ubiquitination PhosphoSitePlus
K99 Ubiquitination PhosphoSitePlus
C101 Methylation IEDB 31844290
T106 Phosphorylation PhosphoSitePlus
S111 Phosphorylation PhosphoSitePlus
K119 Ubiquitination PhosphoSitePlus
S130 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 21406692, 23186163, ...16964243, 18669648, 20068231
K132 Ubiquitination PhosphoSitePlus
C134 Methylation IEDB 31844290
S140 Phosphorylation PhosphoSitePlus
R150 Methylation PhosphoSitePlus
K154 Acetylation PhosphoSitePlus
K154 Ubiquitination PhosphoSitePlus
T158 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S161 Phosphorylation PhosphoSitePlus
K164 Acetylation PhosphoSitePlus
K164 Ubiquitination PhosphoSitePlus
Y166 Phosphorylation PhosphoSitePlus
S183 Phosphorylation PhosphoSitePlus
R184 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S130 Phosphorylation HPRD 18691976, 16964243, 18767875, ...19664994, 19664995, 19651622, 17322306, 18669648, 20068231
S140 Phosphorylation HPRD 19691289
T158 Phosphorylation HPRD 18669648, 20068231
S161 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T39 N39 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S64 F64 Biomuta DOID:4159 / skin cancer [ cosmic ]
R65 Q65 Biomuta DOID:363 / uterine cancer [ icgc ]
S130 F130 Biomuta DOID:4159 / skin cancer [ cosmic ]
R184 P184 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]