Protein Information

Cytoscape View


UniProt AC / UniProt ID Q06455 / MTG8_HUMAN
Protein Name Protein CBFA2T1
Gene Name Name: RUNX1T1
Synonyms:AML1T1,CBFA2T1,CDR,ETO,MTG8,ZMYND2;
Organism Homo sapiens (Human)

PRO ID PR:Q06455
DAG View
PRO Name protein CBFA2T1 (human)
Definition A protein CBFA2T1 that is encoded in the genome of human.
Short Label hRUNX1T1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q06455 (RUNX1T1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S41 Phosphorylation PhosphoSitePlus   UniProt 21406692
T47 Phosphorylation PhosphoSitePlus
T52 Phosphorylation PhosphoSitePlus
T55 Phosphorylation PhosphoSitePlus
S277 Phosphorylation PhosphoSitePlus
S417 Phosphorylation PhosphoSitePlus   UniProt 21406692
K448 Ubiquitination PhosphoSitePlus
K457 Ubiquitination PhosphoSitePlus
T462 Phosphorylation PhosphoSitePlus
S590 Phosphorylation PhosphoSitePlus
T591 Phosphorylation PhosphoSitePlus
T592 Phosphorylation PhosphoSitePlus
T595 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S417 Phosphorylation HPRD 19664995
S590 Phosphorylation HPRD 19664995
T591 Phosphorylation HPRD 19664995
T592 Phosphorylation HPRD 19413330, 19664995
T595 Phosphorylation HPRD 19413330, 19664995
Site PTM Type PTM Enzyme Score Source PMID
S390 Phosphorylation HPRD 19664995
S563 Phosphorylation HPRD 19664995
T564 Phosphorylation HPRD 19664995
T565 Phosphorylation HPRD 19413330, 19664995
T568 Phosphorylation HPRD 19413330, 19664995
Site PTM Type PTM Enzyme Score Source PMID
S380 Phosphorylation HPRD 19664995
S553 Phosphorylation HPRD 19664995
T554 Phosphorylation HPRD 19664995
T555 Phosphorylation HPRD 19413330, 19664995
T558 Phosphorylation HPRD 19413330, 19664995


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T55 S55 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
T462 K462 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]