iPTMnet Report for Q06455 (RUNX1T1)
Protein Information
UniProt AC / UniProt ID | Q06455 / MTG8_HUMAN |
Protein Name | Protein CBFA2T1 |
Gene Name | Name: RUNX1T1 Synonyms:AML1T1,CBFA2T1,CDR,ETO,MTG8,ZMYND2; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q06455 |
PRO Name | protein CBFA2T1 (human) |
Definition | A protein CBFA2T1 that is encoded in the genome of human. |
Short Label | hRUNX1T1 |
Category | organism-gene |
Q06455 (RUNX1T1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S41 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692 | ||
T47 | Phosphorylation | score1 | PhosphoSitePlus | |||
T52 | Phosphorylation | score1 | PhosphoSitePlus | |||
T55 | Phosphorylation | score1 | PhosphoSitePlus | |||
S277 | Phosphorylation | score1 | PhosphoSitePlus | |||
S417 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692 | ||
K448 | Ubiquitination | score1 | PhosphoSitePlus | |||
K457 | Ubiquitination | score1 | PhosphoSitePlus | |||
T462 | Phosphorylation | score1 | PhosphoSitePlus | |||
S590 | Phosphorylation | score1 | PhosphoSitePlus | |||
T591 | Phosphorylation | score1 | PhosphoSitePlus | |||
T592 | Phosphorylation | score1 | PhosphoSitePlus | |||
T595 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S417 | Phosphorylation | score0 | HPRD | 19664995 | ||
S590 | Phosphorylation | score0 | HPRD | 19664995 | ||
T591 | Phosphorylation | score0 | HPRD | 19664995 | ||
T592 | Phosphorylation | score0 | HPRD | 19413330, 19664995 | ||
T595 | Phosphorylation | score0 | HPRD | 19413330, 19664995 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S41 | L41 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
T47 | M47 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ] | |
T55 | S55 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S380 | N380 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S390 | N390 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S417 | N417 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
K457 | R457 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
T462 | K462 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S553 | P553 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
T554 | S554 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S563 | P563 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
T564 | S564 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S590 | P590 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
T591 | S591 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |