iPTMnet Report for Q06418 (TYRO3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q06418 / TYRO3_HUMAN
Protein Name Tyrosine-protein kinase receptor TYRO3 precursor
Gene Name Name: TYRO3
Synonyms:BYK,DTK,RSE,SKY,TIF;
Organism Homo sapiens (Human)

PRO ID PR:Q06418
DAG View
PRO Name tyrosine-protein kinase receptor TYRO3 (human)
Definition A tyrosine-protein kinase receptor TYRO3 that is encoded in the genome of human.
Short Label hTYRO3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q06418 (TYRO3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S6 Phosphorylation RLIMS-P 30765874
N63 N-Glycosylation GlyGen 29391424
N230 N-Glycosylation GlyGen 29391424
N240 N-Glycosylation GlyGen 29391424
S307 Phosphorylation PhosphoSitePlus
N366 N-Glycosylation GlyGen 29391424
N380 N-Glycosylation GlyGen 29391424
T427 Phosphorylation PhosphoSitePlus
S428 Phosphorylation PhosphoSitePlus
S466 Phosphorylation PhosphoSitePlus   UniProt 23186163
K507 Ubiquitination PhosphoSitePlus
K526 Ubiquitination PhosphoSitePlus
S543 Phosphorylation PhosphoSitePlus
K582 Ubiquitination PhosphoSitePlus
Y681 Phosphorylation PhosphoSitePlus
S682 Phosphorylation PhosphoSitePlus
Y685 Phosphorylation PhosphoSitePlus
Y686 Phosphorylation PhosphoSitePlus
S818 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y828 Phosphorylation PhosphoSitePlus
S835 Phosphorylation PhosphoSitePlus
Y849 Phosphorylation PhosphoSitePlus
S869 Phosphorylation HPRD   PhosphoSitePlus 18691976


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N240 I240 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S307 P307 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S307 F307 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
K507 * Biomuta DOID:1319 / brain cancer [ cosmic ]