iPTMnet Report for Q06323 (PSME1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q06323 / PSME1_HUMAN
Protein Name Proteasome activator complex subunit 1
Gene Name Name: PSME1
Synonyms:IFI5111;
Organism Homo sapiens (Human)

PRO ID PR:Q06323
DAG View
PRO Name proteasome activator complex subunit 1 (human)
Definition A proteasome activator complex subunit 1 that is encoded in the genome of human.
Short Label hPSME1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q06323 (PSME1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K13 Acetylation PhosphoSitePlus
K13 Ubiquitination PhosphoSitePlus
T23 Phosphorylation PhosphoSitePlus
K24 Ubiquitination PhosphoSitePlus
T25 Phosphorylation PhosphoSitePlus
S31 Phosphorylation PhosphoSitePlus
K35 Acetylation PhosphoSitePlus
K35 Ubiquitination PhosphoSitePlus
K36 Ubiquitination PhosphoSitePlus
S38 Phosphorylation PhosphoSitePlus
K45 Ubiquitination PhosphoSitePlus
S55 Phosphorylation PhosphoSitePlus
K58 Sumoylation PhosphoSitePlus
K58 Ubiquitination PhosphoSitePlus
K90 Acetylation PhosphoSitePlus
K109 Ubiquitination PhosphoSitePlus
K155 Ubiquitination PhosphoSitePlus
S175 Phosphorylation PhosphoSitePlus
K176 Ubiquitination PhosphoSitePlus
K187 Ubiquitination PhosphoSitePlus
K190 Ubiquitination PhosphoSitePlus
Y209 Phosphorylation PhosphoSitePlus
R213 Methylation PhosphoSitePlus
R220 Methylation PhosphoSitePlus
K232 Acetylation PhosphoSitePlus
K245 Ubiquitination PhosphoSitePlus
Y249 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S238 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K13 N13 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K24 N24 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K45 N45 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S55 G55 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
K90 N90 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
R220 C220 Biomuta [ cosmic ]
Y249 H249 Biomuta DOID:9256 / colorectal cancer [ cosmic ]