iPTMnet Report for Q06278 (AOX1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q06278 / AOXA_HUMAN
Protein Name Aldehyde oxidase
Gene Name Name: AOX1
Synonyms:AO;
Organism Homo sapiens (Human)

PRO ID PR:Q06278
DAG View
PRO Name aldehyde oxidase (human)
Definition An aldehyde oxidase that is encoded in the genome of human.
Short Label hAOX1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q06278 (AOX1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y59 Phosphorylation PhosphoSitePlus
S198 Phosphorylation PhosphoSitePlus
T269 Phosphorylation PhosphoSitePlus
S270 Phosphorylation PhosphoSitePlus
S347 Phosphorylation PhosphoSitePlus
Y527 Phosphorylation PhosphoSitePlus
S531 Phosphorylation PhosphoSitePlus
Y542 Phosphorylation PhosphoSitePlus
Y549 Phosphorylation PhosphoSitePlus
S551 Phosphorylation PhosphoSitePlus
S558 Phosphorylation PhosphoSitePlus
Y697 Phosphorylation PhosphoSitePlus
K722 Ubiquitination PhosphoSitePlus
T814 Phosphorylation PhosphoSitePlus
T821 Phosphorylation PhosphoSitePlus
Y851 Phosphorylation PhosphoSitePlus
K965 Ubiquitination PhosphoSitePlus
S984 Phosphorylation PhosphoSitePlus
S1068 Phosphorylation PhosphoSitePlus   UniProt 24275569
K1108 Ubiquitination PhosphoSitePlus
T1128 Phosphorylation PhosphoSitePlus
T1307 Phosphorylation PhosphoSitePlus
K1318 Acetylation PhosphoSitePlus
K1318 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S347 F347 Biomuta DOID:1319 / brain cancer [ cosmic ]
Y542 C542 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S551 R551 Biomuta DOID:363 / uterine cancer [ icgc ]
Y697 N697 Biomuta DOID:263 / kidney cancer [ cosmic ]
S984 F984 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S1068 L1068 Biomuta [ cosmic ]